Search results for Inhibin Alpha (INHA) Antibody
Inhibin Alpha (INHA) Antibody, Abbexa, abx006694
INHA Antibody is a Rabbit Polyclonal Antibody against INHA.
Host
Rabbit
Reactivity
Mouse, Rat
Applications
WB, IHC
Conjugation
Unconjugated
Inhibin Alpha (INHA) Antibody, Abbexa, abx032959
The inhibin alpha subunit joins either the beta A or beta B subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumour-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. However, in prostate cancer, expression of the inhibin alpha-subunit gene was suppressed and was not detectable in poorly differentiated tumor cells. Furthermore, because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone.
Host
Rabbit
Reactivity
Human, Mouse
Applications
ELISA, WB, IHC, IF/ICC, FCM
Conjugation
Unconjugated
Inhibin Alpha (INHA) Antibody, Abbexa, abx432868
INHA Antibody is a Goat Polyclonal antibody against INHA.
Host
Goat
Reactivity
Human
Applications
P-ELISA, WB, IF/ICC, FCM
Conjugation
Unconjugated
Inhibin Alpha (INHA) Antibody, Abbexa, abx109909
INHA Antibody is a Rabbit Polyclonal antibody against INHA.
Host
Rabbit
Reactivity
Human
Applications
ELISA, IHC
Conjugation
Unconjugated
Inhibin Alpha (INHA) Antibody, Abbexa, abx415674
Inhibin Alpha (INHA) Antibody is a Mouse Monoclonal antibody against Inhibin Alpha (INHA).
Host
Mouse
Reactivity
Human
Applications
IHC
Conjugation
Unconjugated
Inhibin Alpha (INHA) Antibody, Abbexa, abx010990
INHA (A-inhibin subunit precursor, inhibin alpha subunit), also called inhibin (alpha),which is located on chromosome 2q33-q36. Inhibin is a gonadal protein that preferentially suppresses the secretion of pituitary follicle-stimulating hormone (FSH). Inhibin comprises of two subunits,Inhibin A and B. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumor suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa cell tumors and can therefore be used as a marker for primary as well as recurrent disease. In addition to their role in endocrine feedback in the reproductive sytem, inhibins subserve local regulatory roles in numerous extragonadal tissues, including brain, adrenal,bone marrow, placenta, and most notably anterior pituitary. Inhibin alpha subunit gene expression is down regulated in human prostate cancer, suggesting a tumor suppressive role.
Host
Mouse
Reactivity
Human
Applications
ELISA, IHC, IF/ICC
Conjugation
Unconjugated
Inhibin Alpha (INHA) Antibody, Abbexa, abx214879
INHA Antibody is a Rabbit Polyclonal against INHA.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, IHC
Conjugation
Unconjugated
Inhibin Alpha (INHA) Antibody, Abbexa, abx010991
Inhibins are peptide hormones produced by the granulosa cells in female follicles and by Sertoli cells in the male seminiferous tubules. They are selectively expressed by cells of sex cord stromal derivation, and inhibit the secretion of follitropin by the pituitary gland. Inhibins are also involved in regulating diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins, as inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibin has 2 subunits (alpha and beta) that are coded by separate genes. The alpha subunit determines whether inhibin or activin will be produced. The alpha subunit remains constant, such that the various types of inhibin are defined by the beta subunit (a,b,c,d). Inhibin A is a dimer of alpha and beta A. Inhibin B is a dimer of alpha and beta B. Proteolytic processing yields a number of inhibin alpha bioactive forms: the 20/23 kDa forms consist solely of the mature alpha chain, the 26/29 kDa forms consist of the most N terminal propeptide linked through a disulfide bond to the mature alpha chain, and the 50/53 kDa forms encompass the entire proprotein. Each type can be furthermore either mono or diglycosylated, causing the mass difference.
Host
Mouse
Reactivity
Human, Mouse
Applications
ELISA, WB, IF/ICC
Conjugation
Unconjugated
Inhibin Alpha (INHA) Antibody, Abbexa, abx214434
INHA Antibody is a Rabbit Polyclonal against INHA.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, IHC
Conjugation
Unconjugated
Inhibin Alpha (INHA) Antibody (FITC), Abbexa, abx106974
INHA Antibody (FITC) is a Rabbit Polyclonal antibody against INHA conjugated to FITC.
Host
Rabbit
Reactivity
Human
Applications
Conjugation
FITC
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