Search results for Inhibitor of Nuclear Factor Kappa B Kinase Subunit Epsilon (IKBKE) Antibody
Inhibitor Of Nuclear Factor Kappa B Kinase Subunit Epsilon (IKBKE) Antibody, Abbexa, abx212899
IKBKE Antibody is a Rabbit Polyclonal against IKBKE.
Host
Rabbit
Reactivity
Human, Mouse
Applications
ELISA, IHC
Conjugation
Unconjugated
Inhibitor of Nuclear Factor Kappa B Kinase Subunit Epsilon (IKBKE) Antibody, Abbexa, abx010992
Inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon.The transcription factor NF kappa B is retained in the cytoplasm in an inactive form by the inhibitory protein I kappa B. Activation of NF kappa B requires that I kappa B be phosphorylated on specific serine residues, which results in targeted degra-dation of I kappa B. I kappa B kinase alpha (IKK alpha), previously designated CHUK, interacts with I kappa B alpha and specifically phosphorylates I kappa B alpha on the sites that trigger its degradation, serines 32 and 36. The functional IKK complex contains three subunits, IKK alpha, IKK beta and IKK gamma (also designated NEMO), and each appear to make essential contributions to I kappa B phosphorylation. IKK-i is a serine/threonine kinase that shares homology with IKK alpha and IKK beta. IKK-i is pri-marily expressed in immune cells and is induced by lipopolysaccharide and by proinflammatory cytokines including TNF alpha, IL-1 and IL-6. Overexpression of IKK-i was shown to result in phosphorylation of I kappa B alpha on Ser32 and Ser36, and in NF kappa B activation, suggesting that IKK-i may act as an I kappa B kinase in the immune system.
Host
Mouse
Reactivity
Human
Applications
ELISA
Conjugation
Unconjugated
Inhibitor Of Nuclear Factor Kappa B Kinase Subunit Epsilon (IKBKE) Antibody, Abbexa, abx211905
IKBKE Antibody is a Rabbit Polyclonal against IKBKE.
Host
Rabbit
Reactivity
Human, Mouse
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Inhibitor of Nuclear Factor Kappa B Kinase Subunit Epsilon (IKBKE) Antibody, Abbexa, abx216183
Inhibitor of Nuclear Factor Kappa B Kinase Subunit Epsilon (IKBKE) Antibody is a Rabbit Polyclonal antibody for the detection of ikke.
Host
Rabbit
Reactivity
Human, Rat
Applications
ELISA, WB, IHC, IF/ICC
Conjugation
Unconjugated
Inhibitor of Nuclear Factor Kappa B Kinase Subunit Epsilon (IKBKE) Antibody, Abbexa, abx000629
IKBKE Antibody is a Rabbit Polyclonal antibody against IKBKE. IKBKE is a noncanonical I-kappa-B (see MIM 164008) kinase (IKK) that is essential for regulating antiviral signaling pathways. IKBKE has also been identified as a breast cancer (MIM 114480) oncogene and is amplified and overexpressed in over 30% of breast carcinomas and breast cancer cell lines.
Host
Rabbit
Reactivity
Human, Mouse
Applications
WB, IP
Conjugation
Unconjugated
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