Search results for Insulin-like growth factor 1 receptor
Insulin Like Growth Factor 1 Receptor (IGF1R) Antibody, Abbexa, abx012900
Rabbit polyclonal antibody against Insulin Like Growth Factor 1 Receptor (IGF1R) protein. Immunogen region is C-terminal.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Insulin Like Growth Factor 1 Receptor (IGF1R) Antibody, Abbexa, abx128804
Insulin Like Growth Factor 1 Receptor (IGF1R) Antibody is a Rabbit Polyclonal against Insulin Like Growth Factor 1 Receptor (IGF1R).
Host
Rabbit
Reactivity
Human
Applications
WB, IHC, IF/ICC
Conjugation
Unconjugated
Insulin Like Growth Factor 1 Receptor (IGF1R) Antibody, Abbexa, abx176962
This product is currently in development. The lead time for this product may be several months. Please contact us at [email protected] for an updated lead time before purchasing this product. Insulin Like Growth Factor 1 Receptor (IGF1R) Antibody is a Rabbit Polyclonal antibody against Insulin Like Growth Factor 1 Receptor (IGF1R).
Host
Rabbit
Reactivity
Rat
Applications
WB, IHC, IF/ICC
Conjugation
Unconjugated
Insulin Like Growth Factor 1 Receptor (IGF1R) Antibody, Abbexa, abx172914
This product is currently in development. The lead time for this product may be several months. Please contact us at [email protected] for an updated lead time before purchasing this product. Insulin Like Growth Factor 1 Receptor (IGF1R) Antibody is a Mouse Monoclonal antibody against Insulin Like Growth Factor 1 Receptor (IGF1R).
Host
Mouse
Reactivity
Rat
Applications
WB, IHC, IF/ICC
Conjugation
Unconjugated
Insulin Like Growth Factor 1 Receptor (IGF1R) Antibody, Abbexa, abx327744
IGF1R Antibody is a Rabbit Polyclonal against IGF1R.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB
Conjugation
Unconjugated
Insulin Like Growth Factor 1 Receptor (IGF1R) Antibody, Abbexa, abx306436
IGF1R Antibody is a Rabbit Polyclonal against IGF1R.
Host
Rabbit
Reactivity
Human
Applications
ELISA, IF/ICC
Conjugation
Unconjugated
Insulin Like Growth Factor 1 Receptor (IGF1R) Antibody, Abbexa, abx010963
IGF1R (insulin-like growth factor 1 receptor), a transmembrane receptor tyrosine kinase, is widely expressed in many cell types within fetal and postnatal tissues, and in many cell lines. Upon binding to its ligands, IGF-I and IGF-II, receptor autophosphorylation occurs. The triple tyrosine cluster within the kinase domain (Tyr1131, Tyr1135 and Tyr1136) is the earliest major site of autophosphorylation. Phosphorylation of these three tyrosine residues is necessary for kinase activation.Insulin receptors (IRs) share significant similarity with IGF1 receptors in both structure and function,including an equivalent triple tyrosine cluster within the activation loop of the kinase domain (Tyr1146, Tyr1150 and Tyr1151).Tyrosine autophosphorylation of insulin receptor is one of the earliest cellular responses to insulin stimulation. Autophosphorylation begins with phosphorylation of Tyr1146 and either Tyr1150 or Tyr1151. Full kinase activation requires the triple tyrosine phosphorylation.
Host
Mouse
Reactivity
Human
Applications
ELISA, IHC
Conjugation
Unconjugated
Insulin-Like Growth Factor 1 Receptor (IGF1R) Antibody, Abbexa, abx421243
Insulin-Like Growth Factor 1 Receptor (IGF1R) Antibody is a Human Monoclonal antibody for the detection of Insulin-Like Growth Factor 1 Receptor (IGF1R) in Human samples.
Host
Human
Reactivity
Human
Applications
ELISA, WB, FCM
Conjugation
Unconjugated
Insulin Like Growth Factor 1 Receptor (IGF1R) Antibody, Abbexa, abx172913
Insulin Like Growth Factor 1 Receptor (IGF1R) Antibody is a Mouse Monoclonal antibody against Insulin Like Growth Factor 1 Receptor (IGF1R).
Host
Mouse
Reactivity
Human
Applications
WB, IHC, IF/ICC
Conjugation
Unconjugated
Insulin Like Growth Factor 1 Receptor (IGF1R) Antibody, Abbexa, abx000628
Insulin Like Growth Factor 1 Receptor (IGF1R) Antibody is a Rabbit Polyclonal antibody against Insulin Like Growth Factor 1 Receptor (IGF1R). Insulin Like Growth Factor 1 Receptor (IGF1R), also named as CD221, belongs to the protein kinase superfamily, Tyr protein kinase family and Insulin receptor subfamily. Insulin Like Growth Factor 1 Receptor (IGF1R) binds insulin-like growth factor 1 (IGF1) with a high affinity and IGF2 with a lower affinity. It has a tyrosine-protein kinase activity, which is necessary for the activation of the IGF1-stimulated downstream signaling cascade. When present in a hybrid receptor with INSR, Insulin Like Growth Factor 1 Receptor (IGF1R) binds IGF1. The hybrid receptors composed of Insulin Like Growth Factor 1 Receptor (IGF1R) and INSR isoform Long are activated with a high affinity by IGF1, with low affinity by IGF2 and not significantly activated by insulin, and that hybrid receptors composed of Insulin Like Growth Factor 1 Receptor (IGF1R) and INSR isoform Short are activated by IGF1, IGF2 and insulin. In contrast, the hybrid receptors composed of Insulin Like Growth Factor 1 Receptor (IGF1R) and INSR isoform Long and hybrid receptors composed of Insulin Like Growth Factor 1 Receptor (IGF1R) and INSR isoform Short have similar binding characteristics, both bind IGF1 and have a low affinity for insulin. Defects in Insulin Like Growth Factor 1 Receptor (IGF1R) may be a cause in some cases of resistance to insulin-like growth factor 1 (IGF1 resistance). The antibody is specific to Insulin Like Growth Factor 1 Receptor (IGF1R).
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB
Conjugation
Unconjugated
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