Search results for JMJD4 antibody

JMJD4 antibody, Genetex, GTX33277

JMJD4 antibody, Genetex, GTX85252

Jumonji Domain-Containing Protein 4 (JMJD4) Antibody, Abbexa, abx006052

JMJD4 Antibody is a Rabbit Polyclonal Antibody against JMJD4.

Jumonji Domain-Containing Protein 4 (JMJD4) Antibody, Abbexa, abx234441

JMJD4 Antibody is a Rabbit Polyclonal against JMJD4.

Jumonji Domain-Containing Protein 4 (JMJD4) Antibody, Abbexa, abx025007

Covalent modification of histones plays critical role in regulating chromatin structure and transcription. While most covalent histone modifications are reversible, only recently has it been established that methyl groups are subject to enzymatic removal from histones. A family of novel JmjC domain-containing histone demethylation (JHDM) enzymes have been identified that perform this specific function. Histone demethylation by JHDM proteins requires cofactors Fe (II) and alpha-ketoglutarate. Family members include JHDM1 (demethylating histone 3 at lysine 36), and JHDM2A as well as JMJD2CH3K9 (both of which demethylate histone 3 at lysine 9). Contributions of histone demethylase activity to tumor development, decreases in cell proliferation, and hormone-dependent transcriptional activation have been observed.