Search results for JUN (pS73) Antibody
JUN (pS73) Antibody, Abbexa, abx000171
JUN (pS73) Antibody is a Rabbit Polyclonal antibody against JUN (pS73). This gene is the putative transforming gene of avian sarcoma virus 17. It encodes a protein which is highly similar to the viral protein, and which interacts directly with specific target DNA sequences to regulate gene expression. This gene is intronless and is mapped to 1p32-p31, a chromosomal region involved in both translocations and deletions in human malignancies.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
c-Jun (pS73) Antibody, Abbexa, abx000132
c-Jun (pS73) Antibody is a Rabbit Polyclonal antibody against c-Jun (pS73). c-Jun is a member of the Jun Family containing c-Jun, JunB and JunD, and is a component of the transcription factor AP-1 (activator protein-1). AP-1 is composed of dimers of Fos, Jun and ATF family members and binds to and activates transcription at TRE/AP-1 elements (reviewed in 1). Extracellular signals including growth factors, chemokines and stress activate AP-1-dependent transcription. The transcriptional activity of c-Jun is regulated by phosphorylation at Ser63 and Ser73 through SAPK/JNK (reviewed in 2). Knock-out studies in mice have shown that c-Jun is essential for embryogenesis (3), and subsequent studies have demonstrated roles for c-Jun in various tissues and developmental processes including axon regeneration (4), liver regeneration (5) and T cell development (6). AP-1 regulated genes exert diverse biological functions including cell proliferation, differentiation, and apoptosis, as well as transformation, invasion and metastasis, depending on cell type and context (7-9). Other target genes regulate survival as well as hypoxia and angiogenesis (8,10). c-Jun has emerged as a promising therapeutic target for cancer, vascular remodeling, acute inflammation, as well as rheumatoid arthritis (11,12).
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
c-Jun (pS73) Antibody, Abbexa, abx119185
c-Jun (pS73) Antibody is a Rabbit Polyclonal antibody against c-Jun (pS73).
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB, IHC
Conjugation
Unconjugated
Transcription Factor Jun Phospho-Ser73 (JUN pS73) Antibody, Abbexa, abx011039
Transcription Factor Jun Phospho-Ser73 (JUN pS73) Antibody is a Rabbit Polyclonal antibody for the detection of Phospho-Transcription Factor Jun (JUN)（S73）.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Transcription Factor Jun Phospho-Ser73 (JUN pS73) Antibody, Abbexa, abx333266
Jun (pS73) Antibody is a Rabbit Polyclonal against Jun (pS73).
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
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