Search results for Killer Cell Immunoglobulin-Like Receptor 2DS3 (KIR2DS3) Antibody
Killer Cell Immunoglobulin-Like Receptor 2DS3 (KIR2DS3) Antibody, Abbexa, abx240030
Killer Cell Immunoglobulin-Like Receptor 2DS3 (KIR2DS3) Antibody is a Rabbit Polyclonal antibody for the detection of KIR2DS3.
Host
Rabbit
Reactivity
Human, Mouse
Applications
ELISA, IHC
Conjugation
Unconjugated
Killer Cell Immunoglobulin-Like Receptor 2DS3 (KIR2DS3) Antibody, Abbexa, abx032609
Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several 'framework' genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules; thus, KIR proteins are thought to play an important role in regulation of the immune response.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC, FCM
Conjugation
Unconjugated
Killer Cell Immunoglobulin-Like Receptor 2DS3 (KIR2DS3) Antibody, Abbexa, abx301068
KIR2DS3 Antibody is a Rabbit Polyclonal against KIR2DS3.
Host
Rabbit
Reactivity
Human
Applications
ELISA, IF/ICC
Conjugation
Unconjugated
Please provide the required information below so that we can quickly source your products.