Search results for LATS1 antibody

LATS1 antibody, Genetex, GTX131532

LATS1 antibody, Genetex, GTX66748

LATS1 Antibody (YA5996), MedChemexpress, HY-P86304

LATS1 Antibody (YA5996) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to LATS1.

LATS1 Antibody#9153, Cell Signaling Technology (CST), 9153

LATS1 Antibody detects endogenous levels of total LATS1 protein.

Serine/threonine-protein kinase LATS1 antibody, Covalab, Ref 00029131

Large Tumor Suppressor Kinase 1 (LATS1) Antibody, Abbexa, abx210537

LATS1 Antibody is a Rabbit Polyclonal against LATS1.

Large Tumor Suppressor Kinase 1 (LATS1) Antibody, Abbexa, abx312862

LATS1 Antibody is a Rabbit Polyclonal against LATS1.

Large Tumor Suppressor Kinase 1 (LATS1) Antibody, Abbexa, abx234708

LATS1 Antibody is a Rabbit Polyclonal against LATS1.

Large Tumor Suppressor Kinase 1 (LATS1) Antibody, Abbexa, abx113445

Lats, Large Tumor Suppressor, Homolog 1 (Drosophila) Antibody is a Rabbit Polyclonal antibody against Lats, Large Tumor Suppressor, Homolog 1 (Drosophila).

Large Tumor Suppressor Kinase 1 (LATS1) Antibody, Abbexa, abx033135

The protein encoded by this gene is a putative serine/threonine kinase that localizes to the mitotic apparatus and complexes with cell cycle controller CDC2 kinase in early mitosis. The protein is phosphorylated in a cell-cycle dependent manner, with late prophase phosphorylation remaining through metaphase. The N-terminal region of the protein binds CDC2 to form a complex showing reduced H1 histone kinase activity, indicating a role as a negative regulator of CDC2/cyclin A. In addition, the C-terminal kinase domain binds to its own N-terminal region, suggesting potential negative regulation through interference with complex formation via intramolecular binding. Biochemical and genetic data suggest a role as a tumor suppressor. This is supported by studies in knockout mice showing development of soft-tissue sarcomas, ovarian stromal cell tumors and a high sensitivity to carcinogenic treatments.