Search results for Lysine Specific Demethylase 6B (KDM6B) Antibody
Lysine Specific Demethylase 6B (KDM6B) Antibody, Abbexa, abx025643
Covalent modification of histones plays critical role in regulating chromatin structure and transcription. While most covalent histone modifications are reversible, only recently has it been established that methyl groups are subject to enzymatic removal from histones. A family of novel JmjC domain-containing histone demethylation (JHDM) enzymes have been identified that perform this specific function. Histone demethylation by JHDM proteins requires cofactors Fe (II) and alpha-ketoglutarate. Family members include JHDM1 (demethylating histone 3 at lysine 36), and JHDM2A as well as JMJD2CH3K9 (both of which demethylate histone 3 at lysine 9). Contributions of histone demethylase activity to tumor development, decreases in cell proliferation, and hormone-dependent transcriptional activation have been observed.
Host
Rabbit
Reactivity
Mouse
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Lysine Specific Demethylase 6B (KDM6B) Antibody, Abbexa, abx234440
JMJD3 Antibody is a Rabbit Polyclonal against JMJD3.
Host
Rabbit
Reactivity
Human, Mouse
Applications
ELISA, WB
Conjugation
Unconjugated
Lysine Specific Demethylase 6B (KDM6B) Antibody, Abbexa, abx025644
Covalent modification of histones plays critical role in regulating chromatin structure and transcription. While most covalent histone modifications are reversible, only recently has it been established that methyl groups are subject to enzymatic removal from histones. A family of novel JmjC domain-containing histone demethylation (JHDM) enzymes have been identified that perform this specific function. Histone demethylation by JHDM proteins requires cofactors Fe (II) and alpha-ketoglutarate. Family members include JHDM1 (demethylating histone 3 at lysine 36), and JHDM2A as well as JMJD2CH3K9 (both of which demethylate histone 3 at lysine 9). Contributions of histone demethylase activity to tumor development, decreases in cell proliferation, and hormone-dependent transcriptional activation have been observed.
Host
Rabbit
Reactivity
Human, Mouse
Applications
ELISA, WB
Conjugation
Unconjugated
Lysine-Specific Demethylase 6B (KDM6B) Antibody, Abbexa, abx376790
Lysine-Specific Demethylase 6B (KDM6B) Antibody is a Rabbit polyclonal antibody for the detection of Human Lysine-Specific Demethylase 6B (KDM6B).
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
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