Search results for Metadherin (MTDH) Antibody
Metadherin (MTDH) Antibody, Abbexa, abx113692
Metadherin Antibody is a Rabbit Polyclonal antibody against Metadherin.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IHC, IF/ICC
Conjugation
Unconjugated
Metadherin (MTDH) Antibody, Abbexa, abx006805
MTDH Antibody is a Rabbit Polyclonal Antibody against MTDH.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
IHC, IF/ICC
Conjugation
Unconjugated
Metadherin (MTDH) Antibody, Abbexa, abx321360
MTDH Antibody is a Rabbit Polyclonal against MTDH.
Host
Rabbit
Reactivity
Human
Applications
ELISA, IHC, IP
Conjugation
Unconjugated
Metadherin (MTDH) Antibody, Abbexa, abx011143
Metadherin (Metastasis adhesion protein), also known as MTDH, LYsine-RIch CEACAM1 co-isolated (LYRIC), is a novel protein that localizes with the tight junction proteins ZO-1 and occludin in polarized epithelial cells. At the tight junction, it acts not as a structural component, but is rather recruited during the maturation of the tight junction complex. Metadherin is overexpressed in breast cancer tissue and breast tumor xenografts, while much lower levels are expressed in normal breast tissue. Metadherin binds to lung vasculature, one of the four common sites of breast cancer metastasis, through a C-terminal segment in the extracellular domain; blocking this lung-homing domain with antibodies or inhibiting metadherin with siRNA has been reported to inhibit breast cancer metastasis.
Host
Mouse
Reactivity
Human
Applications
ELISA, WB, IHC, FCM
Conjugation
Unconjugated
Metadherin (MTDH) Antibody, Abbexa, abx240125
Metadherin (MTDH) Antibody is a Rabbit Polyclonal antibody for the detection of AEG-1. MTDH, also known as AEG-1, is a single-pass transmembrane protein with its gene located at chromosome 8q22, the abnormalities of which have been identified in several tumor types. MTDH is overexpressed in a number of malignancies, such as breast cancer, malignant glioma, and neuroblastoma, and its overexpression is associated with poor clinical outcome. MTDH plays an important role in the regulation of carcinogenesis and tumor progression. This antibody got two bands about 70 kDa and 80 kDa in western blotting, possibly due to posttranslational modification. This antibody is specific to AEG-1/MTDH.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
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