Search results for Metastasis-Associated Protein MTA2 (MTA2) Antibody
Metastasis-Associated Protein MTA2 (MTA2) Antibody, Abbexa, abx377046
Metastasis-Associated Protein MTA2 (MTA2) Antibody is a Rabbit polyclonal antibody for the detection of Human Metastasis-Associated Protein MTA2 (MTA2).
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Metastasis-Associated Protein MTA2 (MTA2) Antibody, Abbexa, abx001830
MTA2 Antibody is a Rabbit Polyclonal antibody against MTA2. This gene encodes a protein that has been identified as a component of NuRD, a nucleosome remodeling deacetylase complex identified in the nucleus of human cells. It shows a very broad expression pattern and is strongly expressed in many tissues. It may represent one member of a small gene family that encode different but related proteins involved either directly or indirectly in transcriptional regulation. Their indirect effects on transcriptional regulation may include chromatin remodeling. It is closely related to another member of this family, a protein that has been correlated with the metastatic potential of certain carcinomas. These two proteins are so closely related that they share the same types of domains. These domains include two DNA binding domains, a dimerization domain, and a domain commonly found in proteins that methylate DNA. One of the proteins known to be a target protein for this gene product is p53. Deacetylation of p53 is correlated with a loss of growth inhibition in transformed cells supporting a connection between these gene family members and metastasis.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB
Conjugation
Unconjugated
Metastasis-Associated Protein MTA2 (MTA2) Antibody, Abbexa, abx032924
MTA2 is a protein that has been identified as a component of NuRD, a nucleosome remodeling deacetylase complex identified in the nucleus of human cells. It shows a very broad expression pattern and is strongly expressed in many tissues. It may represent one member of a small family of different but related proteins involved either directly or indirectly in transcriptional regulation. Their indirect effects on transcriptional regulation may include chromatin remodeling. It is closely related to another member of this family, a protein that has been correlated with the metastatic potential of certain carcinomas. These two proteins are so closely related that they share the same types of domains. These domains include two DNA binding domains, a dimerization domain, and a domain commonly found in proteins that methylate DNA. One of the proteins known to be a target protein for this gene product is p53. Deacteylation of p53 is correlated with a loss of growth inhibition in transformed cells supporting a connection between these gene family members and metastasis.
Host
Rabbit
Reactivity
Human, Mouse
Applications
ELISA, WB, IHC, FCM
Conjugation
Unconjugated
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