Search results for Methylcytosine Dioxygenase TET2 (TET2) Antibody
Methylcytosine Dioxygenase TET2 (TET2) Antibody, Abbexa, abx238603
TET2 Antibody is a Rabbit Polyclonal against TET2.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Methylcytosine Dioxygenase TET2 (TET2) Antibody, Abbexa, abx001284
TET2 Antibody is a Rabbit Polyclonal antibody against TET2. TET2 (Tet oncogene family member 2), also known as KIAA1546, is a 2,002 amino acid protein that is expressed in a variety of tissues, including brain, kidney, heart, lung, muscle and stomach, and exists as three alternatively spliced isoforms. Murine TET2 is also known as protein Ayu17-449 and is thought to play a role in proper kidney development and overall kidney function, as well as in hormone secretion throughout the body. The gene encoding human TET2 maps to chromosome 4 and the gene encoding mouse TET2 maps to chromosome 3. Chromosome 4 encodes nearly 6% of the human genome and has the largest gene deserts (regions of the genome with no protein encoding genes) of all of the human chromosomes. Defects in some of the genes located on chromosome 4 are associated with Huntington's disease, Ellis-van Creveld syndrome, methylmalonic acidemia and polycystic kidney disease. Murine chromosome 3 houses over 1,300 genes, some of which express alcohol dehydrogenases (ADHs), sodium channel modifiers (SCNMs), interleukins (ILs) and Insulin receptor-related (IRR) proteins. Defects in chromosome 3-localized genes are associated with hereditary congenital facial paresis (HCFP), increased susceptibility to spontaneous colitis, HIV-1-associated nephropathy, decreased renal vascular health and malignant sporadic pancreatic endocrine tumors.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB, IF/ICC
Conjugation
Unconjugated
Methylcytosine Dioxygenase TET2 (TET2) Antibody, Abbexa, abx320625
TET2 Antibody is a Rabbit Polyclonal against TET2.
Host
Rabbit
Reactivity
Human
Applications
ELISA, IHC
Conjugation
Unconjugated
Methylcytosine Dioxygenase TET2 (TET2) Antibody, Abbexa, abx004345
TET2 Antibody is a Rabbit Polyclonal antibody against TET2. The protein encoded by this gene is a methylcytosine dioxygenase that catalyzes the conversion of methylcytosine to 5-hydroxymethylcytosine. The encoded protein is involved in myelopoiesis, and defects in this gene have been associated with several myeloproliferative disorders. Two variants encoding different isoforms have been found for this gene.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB, IHC
Conjugation
Unconjugated
Methylcytosine Dioxygenase TET2 (TET2) Antibody, Abbexa, abx029485
TET2 may catalyze the conversion of methylcytosine (5mC) to 5-hydroxymethylcytosine (hmC) (By similarity). Play an important role in the regulation of myelopoiesis.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
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