Search results for Mitochondrial Antiviral Signaling Protein (MAVS) Antibody
Mitochondrial Antiviral Signaling Protein (MAVS) Antibody, Abbexa, abx211844
MAVS Antibody is a Rabbit Polyclonal against MAVS.
Host
Rabbit
Reactivity
Human, Mouse
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Mitochondrial Antiviral Signaling Protein (MAVS) Antibody, Abbexa, abx405632
This product is currently in development. The lead time for this product may be several months. Please contact us at [email protected] for an updated lead time before purchasing this product. Mouse Mitochondrial Antiviral Signaling Protein (MAVS) Antibody is a Rabbit polyclonal against Mitochondrial Antiviral Signaling Protein (MAVS).
Host
Rabbit
Reactivity
Mouse
Applications
WB, IHC, IF/ICC
Conjugation
Unconjugated
Mitochondrial Antiviral Signaling Protein (MAVS) Antibody, Abbexa, abx113766
Mitochondrial Antiviral Signaling Protein Antibody is a Rabbit Polyclonal antibody against Mitochondrial Antiviral Signaling Protein.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IF/ICC
Conjugation
Unconjugated
Mitochondrial Antiviral Signaling Protein (MAVS) Antibody, Abbexa, abx004412
MAVS Antibody is a Rabbit Polyclonal antibody against MAVS. This gene encodes an intermediary protein necessary in the virus-triggered beta interferon signaling pathways. It is required for activation of transcription factors which regulate expression of beta interferon and contributes to antiviral immunity. Multiple transcript variants encoding different isoforms have been found for this gene.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
IF/ICC
Conjugation
Unconjugated
Mitochondrial Antiviral Signaling Protein (MAVS) Antibody, Abbexa, abx240064
Mitochondrial Antiviral Signaling Protein (MAVS) Antibody is a Rabbit Polyclonal antibody for the detection of MAVS. Required for innate immune defense against viruses. Acts downstream of DDX58/RIG-I and IFIH1/MDA5, which detect intracellular dsRNA produced during viral replication, to coordinate pathways leading to the activation of NF-kappa-B, IRF3 and IRF7, and to the subsequent induction of antiviral cytokines such as IFN-beta and RANTES (CCL5). Peroxisomal and mitochondrial MAVS act sequentially to create an antiviral cellular state. Upon viral infection, peroxisomal MAVS induces the rapid interferon-independent expression of defense factors that provide short-term protection, whereas mitochondrial MAVS activates an interferon-dependent signaling pathway with delayed kinetics, which amplifies and stabilizes the antiviral response. May activate the same pathways following detection of extracellular dsRNA by TLR3. May protect cells from apoptosis.It can undergoe phosphorylation on multiple sites and ubiquitination, which may together cause the molecular weight migrate to about 70 kDa despite the predicated 57 kDa.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Mitochondrial Antiviral Signaling Protein (MAVS) Antibody, Abbexa, abx027604
Double-stranded RNA viruses are recognized in a cell type-dependent manner by the transmembrane receptor TLR3 (MIM 603029) or by the cytoplasmic RNA helicases MDA5 (MIM 606951) and RIGI (ROBO3; MIM 608630). These interactions initiate signaling pathways that differ in their initial steps but converge in the activation of the protein kinases IKKA (CHUK; MIM 600664) and IKKB (IKBKB; MIM 603258), which activate NFKB (see MIM 164011), or TBK1 (MIM 604834) and IKKE (IKBKE; MIM 605048), which activate IRF3 (MIM 603734). Activated IRF3 and NFKB induce transcription of IFNB (IFNB1; MIM 147640). For the TLR3 pathway, the intermediary molecule before the pathways converge is the cytoplasmic protein TRIF (TICAM1; MIM 607601). For RIGI, the intermediary protein is mitochondria-bound IPS1 (Sen and Sarkar, 2005 [PubMed 16239922]).
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB
Conjugation
Unconjugated
Mitochondrial Antiviral Signaling Protein (MAVS) Antibody, Abbexa, abx322215
MAVS Antibody is a Rabbit Polyclonal against MAVS.
Host
Rabbit
Reactivity
Human
Applications
ELISA
Conjugation
Unconjugated
Mitochondrial Antiviral Signaling Protein (MAVS) Antibody, Abbexa, abx213395
MAVS Antibody is a Rabbit Polyclonal against MAVS.
Host
Rabbit
Reactivity
Human, Mouse
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Mitochondrial Antiviral Signaling Protein (MAVS) Antibody, Abbexa, abx404849
Rat Mitochondrial Antiviral Signaling Protein (MAVS) Antibody is a Rabbit polyclonal against Mitochondrial Antiviral Signaling Protein (MAVS).
Host
Rabbit
Reactivity
Rat
Applications
WB, IHC, IF/ICC
Conjugation
Unconjugated
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