Search results for Mitogen-activated protein kinase 7
Mitogen-Activated Protein Kinase 7 / ERK5 (MAPK7) Antibody, Abbexa, abx129556
Mitogen Activated Protein Kinase 7 Antibody is a Rabbit Polyclonal against Mitogen Activated Protein Kinase 7.
Host
Rabbit
Reactivity
Mouse
Applications
WB, IHC, IF/ICC
Conjugation
Unconjugated
Mitogen-Activated Protein Kinase 7 / ERK5 (MAPK7) Antibody, Abbexa, abx033440
MEK5 and ERK5, a member of the MAP kinase subfamily of the Ser/Thr protein kinases, interact specifically with one another and not with MEK1/ERK1 or MEK2/ERK2 pathways. ERK5 is activated by tyrosine and threonine phosphorylation It is expressed in many adult tissues, abundantly in heart, placenta, lung, kidney and skeletal muscle, but is not detectable in liver. The second proline-rich region may interact with actin targeting the kinase to a specific location in the cell. ERK5 is autophosphorylated on threonine and tyrosine residues when the C-terminal part of the kinase, which could have a regulatory role, is absent.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Mitogen-Activated Protein Kinase 7 / ERK5 (MAPK7) Antibody, Abbexa, abx001723
MAPK7 Antibody is a Rabbit Polyclonal antibody against MAPK7. ERK5 (Mitogen-activated protein kinase 7, Big mitogen-activated protein kinase 1) is a member of the MAPK superfamily implicated in the regulation numerous cellular processes including proliferation, differentiation, and survival (1,5-7). Like other MAPK family members, ERK5 contains a canonical activation loop TEY motif (Thr218/Tyr220) which is specifically phosphorylated by MAP2K5 (MEK5) in a growth factor-dependent, Ras-independent mechanism (2-4). For example, EGF stimulation promotes ERK5 phosphorylation which induces its traslocation to the nucleus where it phosphorylates MEF2C and other transcriptional targets (2,3). ERK5 is also activated in response to granulocyte colony-stimulating factor (G-CSF) in hematopoetic progenitor cells where it promotes survival and proliferation (4). In neuronal cells, ERK5 is required for NGF-induced neurite outgrowth, neuronal homeostatis, and survival (11,12). ERK5 is thought to play a role in blood vessel integrity via maintainence of endothelial cell migration and barrier function (8-10). Although broadly expressed, research studies have shown that mice lacking erk5 display numerous cardiac defects, suggesting ERK5 plays a critical role in vascular development and homeostasis (1,5).
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB, IF/ICC
Conjugation
Unconjugated
Mitogen-Activated Protein Kinase 7 / ERK5 (MAPK7) Antibody, Abbexa, abx320116
MAPK7 Antibody is a Rabbit Polyclonal against MAPK7.
Host
Rabbit
Reactivity
Human
Applications
ELISA, IHC, IF/ICC
Conjugation
Unconjugated
Mitogen-Activated Protein Kinase 7 / ERK5 (MAPK7) Antibody, Abbexa, abx113836
Mitogen-Activated Protein Kinase 7 Antibody is a Rabbit Polyclonal antibody against Mitogen-Activated Protein Kinase 7.
Host
Rabbit
Reactivity
Human, Mouse
Applications
ELISA, WB
Conjugation
Unconjugated
Mitogen-Activated Protein Kinase 7 / ERK5 (MAPK7) Antibody, Abbexa, abx234994
MAPK7 Antibody is a Rabbit Polyclonal against MAPK7.
Host
Rabbit
Reactivity
Human, Mouse
Applications
ELISA, WB
Conjugation
Unconjugated
Mitogen-Activated Protein Kinase 7 / ERK5 (MAPK7) Antibody, Abbexa, abx128021
Mitogen Activated Protein Kinase 7 Antibody is a Rabbit Polyclonal against Mitogen Activated Protein Kinase 7.
Host
Rabbit
Reactivity
Human
Applications
WB, IHC, IF/ICC
Conjugation
Unconjugated
Mitogen-Activated Protein Kinase 7 / ERK5 (MAPK7) Antibody, Abbexa, abx242024
MAPK7 Antibody is a Rabbit Polyclonal against MAPK7.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Mitogen-Activated Protein Kinase 7 / ERK5 (MAPK7) Antibody, Abbexa, abx326904
MAPK7 Antibody is a Rabbit Polyclonal against MAPK7.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB, IHC
Conjugation
Unconjugated
Mitogen-Activated Protein Kinase 7 / ERK5 (MAPK7) Antibody, Abbexa, abx234995
MAPK7 Antibody is a Rabbit Polyclonal against MAPK7.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB
Conjugation
Unconjugated
Please provide the required information below so that we can quickly source your products.