Search results for NFkB p65 antibody

NFkB p65 antibody, Genetex, GTX50371

NFkB p65 antibody, Genetex, GTX50374

NFkB p65 antibody, Genetex, GTX102090

NFkB p65 antibody, Genetex, GTX107678

NFkB p65 Antibody, Abbexa, abx012874

Rabbit polyclonal antibody against NF- kappa B p65 protein. Immunogen region is Internal.

NFkB p65 antibody, Genetex, GTX74164

NFkB p65 antibody, Genetex, GTX27970

NFkB p65 Antibody, Abbexa, abx012273

Transcription factors of the nuclear factor kappa B (NF- kappa B)/Rel family is a ubiquitously expressed transcription factor that regulates many cytokine and Ig genes. It is involved in immune, inflammatory, viral, and acute phase responses. There are five family members in mammals: RelA (p65), c-Rel, RelB, NF- kappa B1 (p105/p50) and NF- kappa B2 (p100/p52). The most studied NF- kappa B complex consists of the p50 and p65 subunits, both containing a 300 amino acid region with homology to the Rel proto-oncogene product. The p50 subunit binds DNA, whereas the p65 subunit is responsible for the interaction of NF- kappa B with its inhibitor, I kappa B. In most cell types, the p50/p65 heterodimer is located within the cytoplasm complexed to I kappa B. This complex prevents nuclear translocation and activity of NF- kappa B. In response to stimuli such as cytokines, LPS, and viral infections, I kappa B is phosphorylated at critical residues. This phosphorylation induces dissociation of the I kappa B/NF- kappa B complex, allowing the free heterodimeric NF- kappa B to form a heterotetramer that translocates to the nucleus. In the nucleus, it binds to the kappa B site within promoters and enhancers and functions as a transcriptional activator.

NFkB p65 Antibody (YA5369), MedChemexpress, HY-P85677

NFkB p65 Antibody (YA5369) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to NFkB p65.

NFkB p65 antibody [112A1021], Genetex, GTX13594