Search results for Neuroendocrine Secretory Protein 55 (GNAS) Antibody
Neuroendocrine Secretory Protein 55 (GNAS) Antibody, Abbexa, abx112824
Neuroendocrine Secretory Protein 55 (GNAS) Antibody is a Rabbit Polyclonal antibody against Neuroendocrine Secretory Protein 55 (GNAS). This locus has a highly complex imprinted expression pattern. It gives rise to maternally, paternally, and biallelicall
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB
Conjugation
Unconjugated
Neuroendocrine Secretory Protein 55 (GNAS) Antibody, Abbexa, abx030399
This locus has a highly complex imprinted expression pattern. It gives rise to maternally, paternally, and biallelically expressed transcripts that are derived from four alternative promoters and 5' exons. Some transcripts contains a differentially methylated region (DMR) at their 5' exons, and this DMR is commonly found in imprinted genes and correlates with transcript expression. An antisense transcript is produced from an overlapping locus on the opposite strand. One of the transcripts produced from this locus, and the antisense transcript, are paternally expressed noncoding RNAs, and may regulate imprinting in this region. In addition, one of the transcripts contains a second overlapping ORF, which encodes a structurally unrelated protein Alex. Alternative splicing of downstream exons is also observed, which results in different forms of the stimulatory G-protein alpha subunit, a key element of the classical signal transduction pathway linking receptor-ligand interactions with the activation of adenylyl cyclase and a variety of cellular reponses. Multiple transcript variants encoding different isoforms have been found for this gene. Mutations in this gene result in pseudohypoparathyroidism type 1a, pseudohypoparathyroidism type 1b, Albright hereditary osteodystrophy, pseudopseudohypoparathyroidism, McCune-Albright syndrome, progressive osseus heteroplasia, polyostotic fibrous dysplasia of bone, and some pituitary tumors.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB
Conjugation
Unconjugated
Neuroendocrine Secretory Protein 55 (GNAS) Antibody, Abbexa, abx025024
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The Gs protein is involved in hormonal regulation of adenylate cyclase: it activates the cyclase in response to beta-adrenergic stimuli. Alternative splicing of downstream exons of the GNAS gene is observed, which results in different forms of the stimulatory G protein alpha subunit, a key element of the classical signal transduction pathway linking receptor-ligand interactions with the activatiはn〠oて ちdづnべlべl〠cyclase and a variety of cellular reponses. Multiple transcript variants have been found for this gene, but the full-length nature and/or biological validity of some variants have not been determined. Mutations in this gene result in pseudohypoparathyroidism type 1a, pseudohypoparathyroidism type 1b, Albright hereditary osteodystrophy, pseudopseudohypoparathyroidism, McCune-Albright syndrome, progressive osseus heteroplasia, polyostotic fibrous dysplasia of bone, and some pituitary tumors.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC, IF/ICC, FCM
Conjugation
Unconjugated
Neuroendocrine Secretory Protein 55 (GNAS) Antibody, Abbexa, abx025004
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The Gs protein is involved in hormonal regulation of adenylate cyclase: it activates the cyclase in response to beta-adrenergic stimuli. Alternative splicing of downstream exons of the GNAS gene is observed, which results in different forms of the stimulatory G protein alpha subunit, a key element of the classical signal transduction pathway linking receptor-ligand interactions with the activation of adenylyl cyclase and a variety of cellular reponses. Multiple transcript variants have been found for this gene, but the full-length nature and/or biological validity of some variants have not been determined. Mutations in this gene result in pseudohypoparathyroidism type 1a, pseudohypoparathyroidism type 1b, Albright hereditary osteodystrophy, pseudopseudohypoparathyroidism, McCune-Albright syndrome, progressive osseus heteroplasia, polyostotic fibrous dysplasia of bone, and some pituitary tumors. This antibody is supplied as crude ascites.
Host
Mouse
Reactivity
Mouse
Applications
ELISA, WB
Conjugation
Unconjugated
Neuroendocrine Secretory Protein 55 (GNAS) Antibody, Abbexa, abx431295
Neuroendocrine Secretory Protein 55 (GNAS) Antibody is a Goat Polyclonal antibody against Neuroendocrine Secretory Protein 55 (GNAS).
Host
Goat
Reactivity
Human, Mouse, Rat
Applications
P-ELISA, WB
Conjugation
Unconjugated
Neuroendocrine Secretory Protein 55 (GNAS) Antibody, Abbexa, abx002073
Neuroendocrine Secretory Protein 55 (GNAS) Antibody is a Rabbit Polyclonal antibody against Neuroendocrine Secretory Protein 55 (GNAS). This locus has a highly complex imprinted expression pattern. It gives rise to maternally, paternally, and biallelically expressed transcripts that are derived from four alternative promoters and 5' exons. Some transcripts contain a differentially methylated region (DMR) at their 5' exons, and this DMR is commonly found in imprinted genes and correlates with transcript expression. An antisense transcript is produced from an overlapping locus on the opposite strand. One of the transcripts produced from this locus, and the antisense transcript, are paternally expressed noncoding RNAs, and may regulate imprinting in this region. In addition, one of the transcripts contains a second overlapping ORF, which encodes a structurally unrelated protein - Alex. Alternative splicing of downstream exons is also observed, which results in different forms of the stimulatory G-protein alpha subunit, a key element of the classical signal transduction pathway linking receptor-ligand interactions with the activation of adenylyl cyclase and a variety of cellular reponses. Multiple transcript variants encoding different isoforms have been found for this gene. Mutations in this gene result in pseudohypoparathyroidism type 1a, pseudohypoparathyroidism type 1b, Albright hereditary osteodystrophy, pseudopseudohypoparathyroidism, McCune-Albright syndrome, progressive osseus heteroplasia, polyostotic fibrous dysplasia of bone, and some pituitary tumors. [provided by RefSeq, Aug 2012].
Host
Rabbit
Reactivity
Human, Mouse
Applications
ELISA, WB
Conjugation
Unconjugated
Neuroendocrine Secretory Protein 55 (GNAS) Antibody, Abbexa, abx214658
Neuroendocrine Secretory Protein 55 (GNAS) Antibody is a Rabbit Polyclonal against Neuroendocrine Secretory Protein 55 (GNAS).
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Neuroendocrine Secretory Protein 55 (GNAS) Antibody, Abbexa, abx306646
Neuroendocrine Secretory Protein 55 (GNAS) Antibody is a Rabbit Polyclonal against Neuroendocrine Secretory Protein 55 (GNAS).
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IHC, IF/ICC
Conjugation
Unconjugated
Neuroendocrine Secretory Protein 55 (GNAS) Antibody, Abbexa, abx033029
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G (s) protein is involved in hormonal regulation of adenylate cyclase: it activates the cyclase in response to beta-adrenergic stimuli. XLas isoforms interact with the same set of receptors as Gnas isoforms.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB
Conjugation
Unconjugated
Neuroendocrine Secretory Protein 55 (GNAS) Antibody, Abbexa, abx233536
Neuroendocrine Secretory Protein 55 (GNAS) Antibody is a Rabbit Polyclonal against Neuroendocrine Secretory Protein 55 (GNAS).
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IHC, IP
Conjugation
Unconjugated
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