Search results for Notch1 (C44H11) Rabbit Monoclonal Antibody

Notch1 (C44H11) Rabbit Monoclonal Antibody#3268, Cell Signaling Technology (CST), 3268

Notch1 (C44H11) Rabbit Monoclonal Antibody detects intracellular epitopes between 2400 and 2500 amino acids of human Notch1. This antibody recognizes both the full-length (~300 KDa) and the NTM region (~120 KDa), which consists of a short extracellular juxtamembrane peptide, a transmembrane sequence and the intracellular domain (NICD). This antibody antibody cannot detect the extracellular (ligand-binding) domain of Notch1 following cleavage at the S2 site by ADAM-type metalloproteases.