Search results for Notch1 (D1E11) Rabbit Monoclonal Antibody (BSA and Azide Free)

Notch1 (D1E11) Rabbit Monoclonal Antibody (BSA and Azide Free)#67334, Cell Signaling Technology (CST), 67334

Notch1 (D1E11) Rabbit Monoclonal Antibody (BSA and Azide Free) detects intracellular epitopes between 2400 and 2500 amino acids of human Notch1. This antibody recognizes both the full-length (~300 KDa) and the NTM region (~120 KDa), which consists of a short extracellular juxtamembrane peptide, a transmembrane sequence and the intracellular domain (NICD). This antibody antibody cannot detect the extracellular (ligand-binding) domain of Notch1 following cleavage at the S2 site by ADAM-type metalloproteases.