Search results for PUMA antibody

PUMA antibody, Genetex, GTX13689

PUMA antibody, Covalab, Ref 00101407

PUMA antibody, Covalab, Ref 00101550

PUMA antibody, Genetex, GTX29643

PUMA antibody, Genetex, GTX29645

PUMA antibody, Genetex, GTX70455

PUMA Antibody (YA6021), MedChemexpress, HY-P86329

PUMA Antibody (YA6021) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to PUMA.

PUMA Antibody (YA116), MedChemexpress, HY-P80289

PUMA Antibody (YA116) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to PUMA.

Puma Antibody#4976, Cell Signaling Technology (CST), 4976

Puma Antibody detects endogenous levels of total Puma protein. This antibody also cross-reacts with an 18kDa band of unknown origin.

Anti-PUMA antibody, Abcam, AB9643

Apoptosis is related to many diseases and development. The p53 tumor-suppressor protein induces apoptosis through transcriptional activation of several genes. A novel p53 inducible pro-apoptotic gene was identified recently and designated PUMA (for p53 upregulated modulator of apoptosis) and bbc3 (for Bcl-2 binding component 3) in human and mouse (1-3). PUMA/bbc3 is one of the pro-apoptotic Bcl-2 family members including Bax and Noxa, which are also transcriptional targets of p53. The PUMA gene encodes two BH3 domain-containing proteins termed PUMA-a and PUMA-b (1). PUMA proteins bind Bcl-2, localize to the mitochondria, and induce cytochrome c release and apoptosis in response to p53. PUMA may be a direct mediator of p53-induced apoptosis.