Search results for Phosphatidylinositol 3-Kinase Regulatory Subunit Beta (PIK3R2) Antibody
Phosphatidylinositol 3-Kinase Regulatory Subunit Beta (PIK3R2) Antibody, Abbexa, abx033829
Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. PIK3R2 binds to activated Protein Tyrosine Kinases, which are phosphorylated, through its SH2 domain, and acts as an adaptor, mediating the association of the P110 catalytic unit to the plasma membrane.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Phosphatidylinositol 3-Kinase Regulatory Subunit Beta (PIK3R2) Antibody, Abbexa, abx033830
Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. The family has been classified into 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. PIK3R2 binds to activated Protein Tyrosine Kinases, which are phosphorylated, through its SH2 domain, and acts as an adaptor, mediating the association of the P110 catalytic unit to the plasma membrane.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB
Conjugation
Unconjugated
Phosphatidylinositol 3-Kinase Regulatory Subunit Beta (PIK3R2) Antibody, Abbexa, abx302548
PIK3R2 Antibody is a Rabbit Polyclonal against PIK3R2.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Phosphatidylinositol 3-Kinase Regulatory Subunit Beta (PIK3R2) Antibody, Abbexa, abx037630
Rabbit Polyclonal against the PIK3R2 protein.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Phosphatidylinositol 3-Kinase Regulatory Subunit Beta (PIK3R2) Antibody, Abbexa, abx412806
Phosphatidylinositol 3-Kinase Regulatory Subunit Beta (PIK3R2) Antibody is a Mouse Monoclonal antibody against PI-3 KINASE p85 SUBUNIT BETA.
Host
Mouse
Reactivity
Cow
Applications
WB, IHC, IP
Conjugation
Unconjugated
Phosphatidylinositol 3-Kinase Regulatory Subunit Beta (PIK3R2) Antibody, Abbexa, abx217773
Phosphatidylinositol 3-Kinase Regulatory Subunit Beta (PIK3R2) Antibody is a Rabbit Polyclonal antibody for the detection of PIK3R2. Phosphatidylinositol 3-kinase (PI3K) plays an important role in the metabolic actions of insulin and is required for adipogenesis. The PI3K pathway has also been identified as an important player in cancer development and progression. The Class IA PI3K heterodimer, which is composed of a P110 catalytic subunit and a P85 regulatory subunit, is activated upon association of the P85 subunit with upstream adaptor proteins or receptor tyrosine kinases. Mutations in PIK3R1 are implicated in cases of breast cancer and associated to SHORT syndrome.
Host
Rabbit
Reactivity
Human, Rat
Applications
ELISA, WB
Conjugation
Unconjugated
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