Search results for Piezo-Type Mechanosensitive Ion Channel Component 2 (PIEZO2) Antibody
Piezo-Type Mechanosensitive Ion Channel Component 2 (PIEZO2) Antibody, Abbexa, abx240142
Piezo-Type Mechanosensitive Ion Channel Component 2 (PIEZO2) Antibody is a Rabbit Polyclonal antibody for the detection of Piezo2. The protein encoded by this gene contains more than thirty transmembrane domains and likely functions as part of mechanically-activated (MA) cation channels. These channels serve to connect mechanical forces to biological signals. The encoded protein quickly adapts MA currents in somatosensory neurons. Defects in this gene are a cause of type 5 distal arthrogryposis. Several alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.
Host
Rabbit
Reactivity
Human
Applications
ELISA, IHC
Conjugation
Unconjugated
Piezo-Type Mechanosensitive Ion Channel Component 2 (PIEZO2) Antibody, Abbexa, abx028732
Piezos are large transmembrane proteins conserved among various species, all having between 24 and 36 predicted transmembrane domains. 'Piezo' comes from the Greek 'piesi, ' meaning 'pressure.' The PIEZO2 protein has a role in rapidly adapting mechanically activated (MA) currents in somatosensory neurons (Coste et al., 2010 [PubMed 20813920]).
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB
Conjugation
Unconjugated
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