Search results for Prosaposin (PSAP) Antibody
Prosaposin (PSAP) Antibody, Abbexa, abx128978
Prosaposin Antibody is a Rabbit Polyclonal against Prosaposin.
Host
Rabbit
Reactivity
Human
Applications
WB, IHC, IF/ICC
Conjugation
Unconjugated
Prosaposin (PSAP) Antibody, Abbexa, abx377414
Prosaposin (PSAP) Antibody is a Rabbit polyclonal antibody for the detection of Human Prosaposin (PSAP).
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Prosaposin (PSAP) Antibody, Abbexa, abx001503
PSAP Antibody is a Rabbit Polyclonal antibody against PSAP. The PSAP gene encodes prosaposin, a precursor of four small nonenzymatic glycoproteins termed 'sphingolipid activator proteins' (SAPs) that assist in the lysosomal hydrolysis of sphingolipids. After proteolytic processing of the presaposin protein, these 4 released polypeptides are functional activators. Saposin A is encoded by residues 60 to 143 of PSAP, saposin B by 195 to 275, saposin C by 311 to 390, and saposin D by 405 to 487. They are four 12-14 kDa heatstable glycoproteins. Saposins A-D localize primarily to the lysosomal compartment where they facilitate the catabolism of glycosphingolipids with short oligosaccharide groups. Saposins A-D are required for the hydrolysis of certain sphingolipids by specific lysosomal hydrolases. (PMID: 2001789) Defects in PSAP are the cause of Gaucher disease, Tay-Sachs disease, and metachromatic leukodystrophy (PubMed: 2060627, PMID: 15773042). This PSAP antibody (10801-1-AP) is expected to recognize both saposin A and B.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB, IHC, IF/ICC
Conjugation
Unconjugated
Prosaposin (PSAP) Antibody, Abbexa, abx404005
Human Prosaposin (PSAP) Antibody is a Mouse monoclonal against Prosaposin (PSAP).
Host
Mouse
Reactivity
Human
Applications
WB, IHC, IF/ICC
Conjugation
Unconjugated
Prosaposin (PSAP) Antibody, Abbexa, abx174206
Prosaposin (PSAP) Antibody is a Mouse Monoclonal antibody against Prosaposin (PSAP).
Host
Mouse
Reactivity
Human
Applications
WB, IHC, IF/ICC
Conjugation
Unconjugated
Prosaposin (PSAP) Antibody, Abbexa, abx236840
PSAP Antibody is a Rabbit Polyclonal against PSAP.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IHC, IF/ICC
Conjugation
Unconjugated
Prosaposin (PSAP) Antibody, Abbexa, abx110114
Prosaposin Antibody is a Rabbit Polyclonal antibody against Prosaposin.
Host
Rabbit
Reactivity
Human, Mouse
Applications
ELISA, WB, IHC, IF/ICC
Conjugation
Unconjugated
Prosaposin (PSAP) Antibody, Abbexa, abx011980
This gene encodes a highly conserved glycoprotein which is a precursor for 4 cleavage products: saposins A, B, C, and D. Each domain of the precursor protein is approximately 80 amino acid residues long with nearly identical placement of cysteine residues and glycosylation sites. Saposins A-D localize primarily to the lysosomal compartment where they facilitate the catabolism of glycosphingolipids with short oligosaccharide groups. The precursor protein exists both as a secretory protein and as an integral membrane protein and has neurotrophic activities. Mutations in this gene have been associated with Gaucher disease, Tay-Sachs disease, and metachromatic leukodystrophy. Alternative splicing results in multiple transcript variants encoding different isoforms.
Host
Mouse
Reactivity
Human
Applications
ELISA, IHC, IF/ICC, FCM
Conjugation
Unconjugated
Prosaposin (PSAP) Antibody, Abbexa, abx236841
PSAP Antibody is a Rabbit Polyclonal against PSAP.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IHC, IF/ICC
Conjugation
Unconjugated
Prosaposin (PSAP) Antibody, Abbexa, abx236844
PSAP Antibody is a Rabbit Polyclonal against PSAP.
Host
Rabbit
Reactivity
Human, Mouse
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
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