Search results for Protein Kinase, CGMP Dependent Type I (PRKG1) Antibody
Protein Kinase, CGMP Dependent Type I (PRKG1) Antibody, Abbexa, abx236786
PRKG1 Antibody is a Rabbit Polyclonal against PRKG1.
Host
Rabbit
Reactivity
Human, Mouse
Applications
ELISA, WB, IHC, IF/ICC
Conjugation
Unconjugated
Protein Kinase, CGMP Dependent Type I (PRKG1) Antibody, Abbexa, abx322209
PRKG1 Antibody is a Rabbit Polyclonal against PRKG1.
Host
Rabbit
Reactivity
Human, Mouse
Applications
ELISA, WB
Conjugation
Unconjugated
Protein Kinase, CGMP Dependent Type I (PRKG1) Antibody, Abbexa, abx002002
PRKG1 Antibody is a Rabbit Polyclonal antibody against PRKG1. Mammals have three different isoforms of cyclic GMP-dependent protein kinase (Ialpha, Ibeta, and II). These PRKG isoforms act as key mediators of the nitric oxide/cGMP signaling pathway and are important components of many signal transduction processes in diverse cell types. This PRKG1 gene on human chromosome 10 encodes the soluble Ialpha and Ibeta isoforms of PRKG by alternative transcript splicing. A separate gene on human chromosome 4, PRKG2, encodes the membrane-bound PRKG isoform II. The PRKG1 proteins play a central role in regulating cardiovascular and neuronal functions in addition to relaxing smooth muscle tone, preventing platelet aggregation, and modulating cell growth. This gene is most strongly expressed in all types of smooth muscle, platelets, cerebellar Purkinje cells, hippocampal neurons, and the lateral amygdala. Isoforms Ialpha and Ibeta have identical cGMP-binding and catalytic domains but differ in their leucine/isoleucine zipper and autoinhibitory sequences and therefore differ in their dimerization substrates and kinase enzyme activity.
Host
Rabbit
Reactivity
Human, Mouse
Applications
ELISA, WB
Conjugation
Unconjugated
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