Search results for Protein Kinase cAMP-Dependent Type II Regulatory Subunit Beta (PRKAR2B) Antibody
Protein Kinase cAMP-Dependent Type II Regulatory Subunit Beta (PRKAR2B) Antibody, Abbexa, abx114814
Protein Kinase, Camp-Dependent, Regulatory, Type Ii, Beta Antibody is a Rabbit Polyclonal antibody against Protein Kinase, Camp-Dependent, Regulatory, Type Ii, Beta.
Host
Rabbit
Reactivity
Human, Mouse, Rat, Zebrafish
Applications
ELISA, WB, IHC, IF/ICC
Conjugation
Unconjugated
Protein Kinase cAMP-Dependent Type II Regulatory Subunit Beta (PRKAR2B) Antibody, Abbexa, abx028447
cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation of different target proteins. The inactive kinase holoenzyme is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. The protein encoded by this gene is one of the regulatory subunits. This subunit can be phosphorylated by the activated catalytic subunit. This subunit has been shown to interact with and suppress the transcriptional activity of the cAMP responsive element binding protein 1 (CREB1) in activated T cells. Knockout studies in mice suggest that this subunit may play an important role in regulating energy balance and adiposity. The studies also suggest that this subunit may mediate the gene induction and cataleptic behavior induced by haloperidol. [provided by RefSeq].
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB
Conjugation
Unconjugated
Protein Kinase cAMP-Dependent Type II Regulatory Subunit Beta (PRKAR2B) Antibody, Abbexa, abx037073
Rabbit Polyclonal against the PRKAR2B protein.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
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