Search results for Protein SET (SET) Antibody
Protein SET (SET) Antibody, Abbexa, abx430042
SET Antibody is a Goat Polyclonal antibody against SET.
Host
Goat
Reactivity
Human
Applications
P-ELISA, WB
Conjugation
Unconjugated
Protein SET (SET) Antibody, Abbexa, abx237764
SET Antibody is a Rabbit Polyclonal against SET.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Protein SET (SET) Antibody, Abbexa, abx004747
SET Antibody is a Rabbit Polyclonal antibody against SET. The protein encoded by this gene inhibits acetylation of nucleosomes, especially histone H4, by histone acetylases (HAT). This inhibition is most likely accomplished by masking histone lysines from being acetylated, and the consequence is to silence HAT-dependent transcription. The encoded protein is part of a complex localized to the endoplasmic reticulum but is found in the nucleus and inhibits apoptosis following attack by cytotoxic T lymphocytes. This protein can also enhance DNA replication of the adenovirus genome. Several transcript variants encoding different isoforms have been found for this gene.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB
Conjugation
Unconjugated
Protein SET (SET) Antibody, Abbexa, abx455775
Protein SET (SET) Antibody is a Rabbit polyclonal antibody for the detection of Human Protein SET (SET).
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Protein SET (SET) Antibody, Abbexa, abx338613
SET Antibody is a Rabbit Polyclonal against SET.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB
Conjugation
Unconjugated
Protein SET (SET) Antibody, Abbexa, abx028158
Multitasking protein, involved in apoptosis, transcription, nucleosome assembly and histone binding. Isoform 2 anti-apoptotic activity is mediated by inhibition of the GZMA-activated DNase, NME1. In the course of cytotoxic T-lymphocyte (CTL) induced apoptosis, GZMA cleaves SET, disrupting its binding to NME1 and releasing NME1 inhibition. Isoform 1 and isoform 2 are potent inhibitors of protein phosphatase 2A. Isoform 1 and isoform 2 inhibit EP300/CREBBP and PCAF-mediated acetylation of histones (HAT) and nucleosomes, most probably by masking the accessibility of lysines of histones to the acetylases. The predominant target for inhibition is histone H4. HAT inhibition leads to silencing of HAT-dependent transcription and prevents active demethylation of DNA. Both isoforms stimulate DNA replication of the adenovirus genome complexed with viral core proteins; however, isoform 2 specific activity is higher.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Protein SET (SET) Antibody (Biotin), Abbexa, abx337314
SET Antibody (Biotin) is a Rabbit Polyclonal against SET.
Host
Rabbit
Reactivity
Human
Applications
ELISA
Conjugation
Biotin
Protein SET (SET) Antibody (FITC), Abbexa, abx337313
SET Antibody (FITC) is a Rabbit Polyclonal against SET.
Host
Rabbit
Reactivity
Human
Applications
Conjugation
FITC
Protein SET (SET) Antibody (HRP), Abbexa, abx337312
SET Antibody (HRP) is a Rabbit Polyclonal against SET.
Host
Rabbit
Reactivity
Human
Applications
ELISA
Conjugation
HRP
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