Search results for Protein Timeless Homolog (TIMELESS) Antibody
Protein Timeless Homolog (TIMELESS) Antibody, Abbexa, abx240110
Protein Timeless Homolog (TIMELESS) Antibody is a Rabbit Polyclonal antibody for the detection of TIMELESS. Plays an important role in the control of DNA replication, maintenance of replication fork stability, maintenance of genome stability throughout normal DNA replication and in the regulation of the circadian clock. Involved in the determination of period length and in the DNA damage-dependent phase advancing of the circadian clock. Negatively regulates CLOCK|NPAS2-ARTNL/BMAL1|ARTNL2/BMAL2-induced transactivation of PER1 possibly via translocation of PER1 into the nucleus. Forms a complex with TIPIN and this complex regulates DNA replication processes under both normal and stress conditions, stabilizes replication forks and influences both CHEK1 phosphorylation and the intra-S phase checkpoint in response to genotoxic stress. Timeless promotes TIPIN nuclear localization. Involved in cell survival after DNA damage or replication stress. May be specifically required for the ATR-CHEK1 pathway in the replication checkpoint induced by hydroxyurea or ultraviolet light. May also play an important role in epithelial cell morphogenesis and formation of branching tubules.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB
Conjugation
Unconjugated
Protein timeless homolog (TIMELESS) Antibody, Abbexa, abx334306
TIMELESS Antibody is a Rabbit Polyclonal against TIMELESS.
Host
Rabbit
Reactivity
Human
Applications
ELISA, IHC
Conjugation
Unconjugated
Protein Timeless Homolog (TIMELESS) Antibody, Abbexa, abx145024
TIMELESS Antibody is a Rabbit Polyclonal against TIMELESS.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB
Conjugation
Unconjugated
Protein Timeless Homolog (TIMELESS) Antibody, Abbexa, abx238694
TIMELESS Antibody is a Rabbit Polyclonal against TIMELESS.
Host
Rabbit
Reactivity
Human, Mouse
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Protein Timeless Homolog (TIMELESS) Antibody, Abbexa, abx003158
TIMELESS Antibody is a Rabbit Polyclonal antibody against TIMELESS. The protein encoded by this gene is highly conserved and is involved in cell survival after damage or stress, increase in DNA polymerase epsilon activity, maintenance of telomere length, and epithelial cell morphogenesis. The encoded protein also plays a role in the circadian rhythm autoregulatory loop, interacting with the PERIOD genes (PER1, PER2, and PER3) and others to downregulate activation of PER1 by CLOCK/ARNTL. Changes in this gene or its expression may promote prostate cancer, lung cancer, breast cancer, and mental disorders.
Host
Rabbit
Reactivity
Human, Mouse
Applications
WB
Conjugation
Unconjugated
Protein Timeless Homolog (TIMELESS) Antibody, Abbexa, abx116104
Timeless Homolog (Drosophila) Antibody is a Rabbit Polyclonal antibody against Timeless Homolog (Drosophila).
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Protein timeless homolog (TIMELESS) Antibody (FITC), Abbexa, abx337322
TIMELESS Antibody (FITC) is a Rabbit Polyclonal against TIMELESS.
Host
Rabbit
Reactivity
Human
Applications
Conjugation
FITC
Protein timeless homolog (TIMELESS) Antibody (Biotin), Abbexa, abx337323
TIMELESS Antibody (Biotin) is a Rabbit Polyclonal against TIMELESS.
Host
Rabbit
Reactivity
Human
Applications
ELISA
Conjugation
Biotin
Protein timeless homolog (TIMELESS) Antibody (HRP), Abbexa, abx337321
TIMELESS Antibody (HRP) is a Rabbit Polyclonal against TIMELESS.
Host
Rabbit
Reactivity
Human
Applications
ELISA
Conjugation
HRP
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