Search results for Purified anti-p63 (TA) Antibody, p63 (TA), TAp63-4.1
Purified anti-p63 (TA) Antibody, p63 (TA), TAp63-4.1, BioLegend, 938101
Epitope binding of TAp63-4.1 has been mapped to the LSDPxW motif at the C-terminal region of the p63 transactivation (TA) domain (Nekulova M,et al.2013.Virchows Arch. 463:415). Because this sequence is absent in the p63 (?N isoform) and the p63 paralog p73, this antibody is not predicted to react with either protein. Lack of p63 (?N) reactivity was confirmed during product development testing.This clone was ICC tested on Raji cells fixed with 4% PFA and permeabilized with either Triton X-100 or methanol. Both methods were compatible with p63 (TA) staining.This clone is predicted to recognize all p63 (TA) isoforms.This clone is predicted to recognize mouse p63 (TA) due to complete sequence conservation of the LSDPxW epitope between human and mouse p63 (TA) orthologs.
Host
Mouse
Reactivity
Human
Applications
WB -Quality testedICC, IP -Verified
Conjugation
Purified anti-p63 (TA) Antibody, p63 (TA), TAp63-4.1, BioLegend, 938102
Epitope binding of TAp63-4.1 has been mapped to the LSDPxW motif at the C-terminal region of the p63 transactivation (TA) domain (Nekulova M,et al.2013.Virchows Arch. 463:415). Because this sequence is absent in the p63 (?N isoform) and the p63 paralog p73, this antibody is not predicted to react with either protein. Lack of p63 (?N) reactivity was confirmed during product development testing.This clone was ICC tested on Raji cells fixed with 4% PFA and permeabilized with either Triton X-100 or methanol. Both methods were compatible with p63 (TA) staining.This clone is predicted to recognize all p63 (TA) isoforms.This clone is predicted to recognize mouse p63 (TA) due to complete sequence conservation of the LSDPxW epitope between human and mouse p63 (TA) orthologs.
Host
Mouse
Reactivity
Human
Applications
WB -Quality testedICC, IP -Verified
Conjugation
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