Search results for RELA (pS536) Antibody
RELA (pS536) Antibody, Abbexa, abx000176
RELA (pS536) Antibody is a Rabbit Polyclonal antibody against RELA (pS536). NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IF/ICC
Conjugation
Unconjugated
RELA (pS536) Antibody, Abbexa, abx032261
NFKB1 (MIM 164011) or NFKB2 (MIM 164012) is bound to REL (MIM 164910), RELA, or RELB (MIM 604758) to form the NFKB complex. The p50 (NFKB1) /p65 (RELA) heterodimer is the most abundant form of NFKB. The NFKB complex is inhibited by I-kappa-B proteins (NFKBIA, MIM 164008 or NFKBIB, MIM 604495), which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the I-kappa-B proteins by kinases (IKBKA, MIM 600664, or IKBKB, MIM 603258) marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NFKB complex. Activated NFKB complex translocates into the nucleus and binds DNA at kappa-B-binding motifs such as 5-prime GGGRNNYYCC 3-prime or 5-prime HGGARNYYCC 3-prime (where H is A, C, or T; R is an A or G purine; and Y is a C or T pyrimidine).
Host
Rabbit
Reactivity
Human
Applications
ELISA, DB
Conjugation
Unconjugated
RELA (pS536) Antibody, Abbexa, abx000518
RELA (pS536) Antibody is a Rabbit Polyclonal antibody against RELA (pS536). NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Transcription Factor p65 Phospho-Ser536 (RELA pS536) Antibody, Abbexa, abx011269
Transcription Factor p65 Phospho-Ser536 (RELA pS536) Antibody is a Rabbit Polyclonal antibody for the detection of Phospho-NF-kB p65-S536.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Transcription Factor p65 Phospho-Ser536 (RELA pS536) Antibody, Abbexa, abx330097
RELA (pS536) Antibody is a Rabbit Polyclonal against RELA (pS536).
Host
Rabbit
Reactivity
Human, Mouse, Rat, Monkey
Applications
ELISA, WB, IHC, IP
Conjugation
Unconjugated
Transcription Factor p65 Phospho-Ser536 (RELA pS536) Antibody, Abbexa, abx333176
RELA (pS536) Antibody is a Rabbit Polyclonal against RELA (pS536).
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IHC, IF/ICC
Conjugation
Unconjugated
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