Search results for Ring Finger Protein 34 (RNF34) Antibody
Ring Finger Protein 34 (RNF34) Antibody, Abbexa, abx115298
Ring Finger Protein 34 Antibody is a Rabbit Polyclonal antibody against Ring Finger Protein 34.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, IHC
Conjugation
Unconjugated
Ring Finger Protein 34 (RNF34) Antibody, Abbexa, abx237355
RNF34 Antibody is a Rabbit Polyclonal against RNF34.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, IHC
Conjugation
Unconjugated
Ring Finger Protein 34 (RNF34) Antibody, Abbexa, abx240012
Ring Finger Protein 34 (RNF34) Antibody is a Rabbit Polyclonal antibody for the detection of RNF34. E3 ubiquitin-protein ligase that regulates several biological processes through the ubiquitin-mediated proteasomal degradation of various target proteins. Ubiquitinates the caspases CASP8 and CASP10, promoting their proteasomal degradation, to negatively regulate cell death downstream of death domain receptors in the extrinsic pathway of apoptosis (PubMed:15069192). May mediate 'Lys-48'-linked polyubiquitination of RIPK1 and its subsequent proteasomal degradation thereby indirectly regulating the tumor necrosis factor-mediated signaling pathway (Ref.13). Negatively regulates p53/TP53 through its direct ubiquitination and targeting to proteasomal degradation (PubMed:17121812). Indirectly, may also negatively regulate p53/TP53 through ubiquitination and degradation of SFN (PubMed:18382127). Mediates PPARGC1A proteasomal degradation probably through ubiquitination thereby indirectly regulating the metabolism of brown fat cells (PubMed:22064484). Possibly involved in innate immunity, through 'Lys-48'-linked polyubiquitination of NOD1 and its subsequent proteasomal degradation (PubMed:25012219).
Host
Rabbit
Reactivity
Human
Applications
WB
Conjugation
Unconjugated
Ring Finger Protein 34 (RNF34) Antibody, Abbexa, abx321014
RNF34 Antibody is a Rabbit Polyclonal against RNF34.
Host
Rabbit
Reactivity
Human
Applications
ELISA, IHC
Conjugation
Unconjugated
Ring Finger Protein 34 (RNF34) Antibody, Abbexa, abx321921
RNF34 Antibody is a Rabbit Polyclonal against RNF34.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Ring Finger Protein 34 (RNF34) Antibody, Abbexa, abx005861
RNF34 Antibody is a Rabbit Polyclonal Antibody against RNF34.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IF/ICC
Conjugation
Unconjugated
Ring Finger Protein 34 (RNF34) Antibody, Abbexa, abx430467
RNF34 Antibody is a Goat Polyclonal antibody against RNF34.
Host
Goat
Reactivity
Human
Applications
P-ELISA, IHC
Conjugation
Unconjugated
Ring Finger Protein 34 (RNF34) Antibody, Abbexa, abx028953
The protein encoded by this gene contains a RINF finger, a motif known to be involved in protein-protein and protein-DNA interactions. This protein interacts with DNAJA3/hTid-1, which is a DnaJ protein reported to function as a modulator of apoptosis. Overexpression of this gene in Hela cells was shown to confer the resistance to TNF-alpha induced apoptosis, suggesting an anti-apoptotic function of this protein. This protein can be cleaved by caspase-3 during the induction of apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB
Conjugation
Unconjugated
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