Search results for SHARPIN antibody

SHARPIN antibody, Genetex, GTX52193

SHARPIN antibody, Genetex, GTX130231

SHARPIN antibody, Genetex, GTX66093

SHARPIN (SHARPIN) Antibody, Abbexa, abx126546

SHARPIN Antibody is a Rabbit Polyclonal against SHARPIN.

SHARPIN (SHARPIN) Antibody, Abbexa, abx338689

SHARPIN Antibody is a Rabbit Polyclonal against SHARPIN.

Anti-SHARPIN antibody, Abcam, AB197853

Anti-SHARPIN antibody, Abcam, AB236092

Anti-SHARPIN antibody, Abcam, AB69507

SHARPIN (SHARPIN) Antibody, Abbexa, abx126547

SHARPIN Antibody is a Rabbit Polyclonal against SHARPIN.

SHARPIN (SHARPIN) Antibody, Abbexa, abx240065

SHARPIN (SHARPIN) Antibody is a Rabbit Polyclonal antibody for the detection of SHARPIN. Component of the LUBAC complex which conjugates linear polyubiquitin chains in a head-to-tail manner to substrates and plays a key role in NF-kappa-B activation and regulation of inflammation. LUBAC conjugates linear polyubiquitin to IKBKG and RIPK1 and is involved in activation of the canonical NF-kappa-B and the JNK signaling pathways. Linear ubiquitination mediated by the LUBAC complex interferes with TNF-induced cell death and thereby prevents inflammation. LUBAC is proposed to be recruited to the TNF-R1 signaling complex (TNF-RSC) following polyubiquitination of TNF-RSC components by BIRC2 and/or BIRC3 and to conjugate linear polyubiquitin to IKBKG and possibly other components contributing to the stability of the complex. Together with FAM105B/otulin, the LUBAC complex regulates the canonical Wnt signaling during angiogenesis.