Search results for STEAP3 Metalloreductase (STEAP3) Antibody
STEAP3 Metalloreductase (STEAP3) Antibody, Abbexa, abx302912
STEAP3 Antibody is a Rabbit Polyclonal against STEAP3.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC, IF/ICC
Conjugation
Unconjugated
STEAP3 Metalloreductase (STEAP3) Antibody, Abbexa, abx028683
Endosomal ferrireductase required for efficient transferrin-dependent iron uptake in erythroid cells. Participates in erythroid iron homeostasis by reducing Fe (3+) to Fe (2+). Can also reduce of Cu (2+) to Cu (1+), suggesting that it participates in copper homeostasis. Uses NAD (+) as acceptor (By similarity). May play a role downstream of p53/TP53 to interface apoptosis and cell cycle progression. Indirectly involved in exosome secretion by facilitating the secretion of proteins such as TCTP.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB
Conjugation
Unconjugated
STEAP3 Metalloreductase (STEAP3) Antibody, Abbexa, abx238318
STEAP3 Antibody is a Rabbit Polyclonal against STEAP3.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IHC, IF/ICC, IP
Conjugation
Unconjugated
STEAP3 Metalloreductase (STEAP3) Antibody, Abbexa, abx000818
STEAP3 Antibody is a Rabbit Polyclonal antibody against STEAP3. Caspases modulate apoptosis in various ways. Specifically, Caspase-3, a death protease, is instrumental in cleaving cellular proteins, dismantling the cell and forming apoptotic bodies. pHyde has a potential role as a tumor suppressor by inducing caspase-3-mediated apoptosis and stimulating p53 expression. A dose-dependent increase in caspase-3 activity is observed in transduced pHyde DU145 cells. Furthermore, caspase-3 may be necessary for pHyde-mediated apoptosis. The pHyde gene may upregulate the apoptosis pathway and thus have a potential application in cancer gene therapy. Recombinant pHyde inhibits the growth of human prostate cancer cell lines DU145 and LNCaP in vitro. DU145 tumors may be reduced significantly in vivo when nude mice are injected with recombinant pHyde. pHyde also has a demonstrated growth inhibitory effect on human breast cancer cells. This suggests that pHyde may have a role in inhibiting different tumor types.
Host
Rabbit
Reactivity
Human, Mouse
Applications
ELISA, WB
Conjugation
Unconjugated
STEAP3 Metalloreductase (STEAP3) Antibody, Abbexa, abx329246
STEAP3 Antibody is a Rabbit Polyclonal against STEAP3.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IHC, IF/ICC
Conjugation
Unconjugated
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