Search results for Serine/threonine-protein kinase Chk2

Serine/Threonine-Protein Kinase Chk2 (CHEK2) Antibody, Abbexa, abx377127

Serine/Threonine-Protein Kinase Chk2 (CHEK2) Antibody is a Rabbit polyclonal antibody for the detection of Human Serine/Threonine-Protein Kinase Chk2 (CHEK2).

Serine/threonine-Protein Kinase Chk2 (CHK2) Antibody, Abbexa, abx010556

CHK2: CHK2 checkpoint homolog (S. pombe). In response to DNA damage and replication blocks, cell cycle progression is halted through the control of critical cell cycle regulators. The protein encoded by this gene is a cell cycle checkpoint regulator and putative tumor suppressor. It contains a forkhead-associated protein interaction domain essential for activation in response to DNA damage and is rapidly phosphorylated in response to replication blocks and DNA damage. When activated, the encoded protein is known to inhibit CDC25C phosphatase, preventing entry into mitosis, and has been shown to stabilize the tumor suppressor protein p53, leading to cell cycle arrest in G1. In addition, this protein interacts with and phosphorylates BRCA1, allowing BRCA1 to restore survival after DNA damage. Mutations in this gene have been linked with Li-Fraumeni syndrome, a highly penetrant familial cancer phenotype usually associated with inherited mutations in TP53. Also, mutations in this gene are thought to confer a predisposition to sarcomas, breast cancer, and brain tumors. This nuclear protein is a member of the CDS1 subfamily of serine/threonine protein kinases. Three transcript variants encoding different isoforms have been found for this gene.

Serine/threonine-Protein Kinase Chk2 (CHK2) Antibody, Abbexa, abx231654

Chk2 Antibody is a Rabbit Polyclonal against Chk2.

Serine/threonine-Protein Kinase Chk2 (CHK2) Antibody, Abbexa, abx012850

Rabbit polyclonal antibody against Chk2 protein. Immunogen region is N-terminal.

Serine/Threonine-Protein Kinase CHK2 Phospho-Thr383 (CHEK2 pT383) Antibody, Abbexa, abx012469

Rabbit polyclonal antibody against Chk2 protein. Immunogen region is Internal. Specificity is as follows for the reactive species: H:T383, M:T387, R:T386.

Chk2 Antibody (YA6186), MedChemexpress, HY-P86494

Chk2 Antibody (YA6186) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Chk2.

CHEK2 Polyclonal Antibody, Bioss, bs-1391R

Phospho-CHEK2 (Thr68) Polyclonal Antibody, Bioss, bs-3721R

Phospho-Chk2 (Thr68) Antibody, MedChemexpress, HY-P80799

Phospho-Chk2 (Thr68) Antibody is a Rabbit-derived and non-conjugated IgG polyclonal antibody, targeting to Phospho-Chk2 (Thr68).

Chk2 (1C12) Mouse Monoclonal Antibody (BSA and Azide Free)#17332, Cell Signaling Technology (CST), 17332

Chk2 (1C12) Mouse Monoclonal Antibody (BSA and Azide Free) detects endogenous levels of total Chk2 protein.