Search results for Sorting Nexin 6 (SNX6) Antibody
Sorting Nexin 6 (SNX6) Antibody, Abbexa, abx028206
SNX6 interacts with members of the transforming growth factor-beta family of receptor serine-threonine kinases. These receptors belong to two classes: type II receptors that bind ligand, and type I receptors that are subsequently recruited to transduce the signal. Of the type II receptors, SNX6 was found to interact strongly with ActRIIB and more moderately with wild type and kinase-defective mutants of TbetaRII. Of the type I receptors, SNX6 was found to interact only with inactivated TbetaRI. SNXs 1-4 also interacted with the transforming growth factor-beta receptor family, showing different receptor preferences. Conversely, SNX6 behaved similarly to the other SNX proteins in its interactions with receptor tyrosine kinases. Strong heteromeric interactions were also seen among SNX1, 2, 4, and 6, suggesting the formation in vivo of oligomeric complexes. These findings are the first evidence for the association of the SNX family of molecules with receptor serine-threonine kinases.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB
Conjugation
Unconjugated
Sorting Nexin 6 (SNX6) Antibody, Abbexa, abx238095
SNX6 Antibody is a Rabbit Polyclonal against SNX6.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Sorting Nexin 6 (SNX6) Antibody, Abbexa, abx025344
This product is currently in development. The lead time for this product may be several months. Please contact us at [email protected] for an updated lead time before purchasing this product. This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein associates with the long isoform of the leptin receptor, the transforming growth factor-beta family of receptor serine-threonine kinases, and with receptor tyrosine kinases for platelet-derived growth factor, insulin, and epidermal growth factor. This protein may form oligomeric complexes with family member proteins through interactions of both the PX domain and the coiled coil regions of the molecules. Translocation of this protein from the cytoplasm to the nucleus occurs after binding to proviral integration site 1 protein. This gene results in two transcripts encoding two distinct isoforms. This antibody is supplied as crude ascites.
Host
Mouse
Reactivity
Human
Applications
ELISA, WB
Conjugation
Unconjugated
Sorting Nexin 6 (SNX6) Antibody, Abbexa, abx135957
SNX6 Antibody is a Rabbit Polyclonal against SNX6.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB
Conjugation
Unconjugated
Sorting Nexin 6 (SNX6) Antibody, Abbexa, abx115742
Sorting Nexin 6 Antibody is a Rabbit Polyclonal antibody against Sorting Nexin 6.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA
Conjugation
Unconjugated
Sorting Nexin 6 (SNX6) Antibody, Abbexa, abx302878
SNX6 Antibody is a Rabbit Polyclonal against SNX6.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Sorting Nexin 6 (SNX6) Antibody, Abbexa, abx028205
SNX6 interacts with members of the transforming growth factor-beta family of receptor serine-threonine kinases. These receptors belong to two classes: type II receptors that bind ligand, and type I receptors that are subsequently recruited to transduce the signal. Of the type II receptors, SNX6 was found to interact strongly with ActRIIB and more moderately with wild type and kinase-defective mutants of TbetaRII. Of the type I receptors, SNX6 was found to interact only with inactivated TbetaRI. SNXs 1-4 also interacted with the transforming growth factor-beta receptor family, showing different receptor preferences. Conversely, SNX6 behaved similarly to the other SNX proteins in its interactions with receptor tyrosine kinases. Strong heteromeric interactions were also seen among SNX1, 2, 4, and 6, suggesting the formation in vivo of oligomeric complexes. These findings are the first evidence for the association of the SNX family of molecules with receptor serine-threonine kinases.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB
Conjugation
Unconjugated
Sorting Nexin 6 (SNX6) Antibody (HRP), Abbexa, abx312154
SNX6 Antibody (HRP) is a Rabbit Polyclonal against SNX6 conjugated to HRP.
Host
Rabbit
Reactivity
Human
Applications
ELISA
Conjugation
HRP
Sorting Nexin 6 (SNX6) Antibody (Biotin), Abbexa, abx312156
SNX6 Antibody (Biotin) is a Rabbit Polyclonal against SNX6 conjugated to Biotin.
Host
Rabbit
Reactivity
Human
Applications
ELISA
Conjugation
Biotin
Sorting Nexin 6 (SNX6) Antibody (FITC), Abbexa, abx312155
SNX6 Antibody (FITC) is a Rabbit Polyclonal against SNX6 conjugated to FITC.
Host
Rabbit
Reactivity
Human
Applications
Conjugation
FITC
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