Search results for Sterol Regulatory Element-Binding Protein 2 (SREBF2) Antibody
Sterol Regulatory Element-Binding Protein 2 (SREBF2) Antibody, Abbexa, abx025838
SREBPs, including SREBP-1a, SREBP-1c, and SREBP-2, constitute a family of basic helix-loop-helix (bHLH) transcription factors that play a critical role in lipid homeostasis by regulating genes involved in cholesterol and fatty acid metabolism. Each SREBP consists of three domains, including an amino-terminal transcription factor domain of ~480 amino acids, a middle hydrophobic region of ~80 amino acids containing two hydrophobic transmembrane segments, and a carboxy-terminal regulatory domain of ~590 amino acids. SREBP-2 regulates cholesterol synthesis by activating the transcription of genes for HMG-CoA reductase and other enzymes of the cholesterol synthetic pathway. SREBP-2 is ubiquitously detected in various tissues. Under basal conditions SREBP is bound to ER membranes as a glycosylated precursor protein. Upon cholesterol depletion, the protein is cleaved to its active forms (about 50-68 kDa) and translocated into the nucleus to stimulate transcription of genes involved in the uptake and synthesis of cholesterol.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC, IF/ICC
Conjugation
Unconjugated
Sterol Regulatory Element-Binding Protein 2 (SREBF2) Antibody, Abbexa, abx115859
Sterol Regulatory Element Binding Transcription Factor 2 Antibody is a Rabbit Polyclonal antibody against Sterol Regulatory Element Binding Transcription Factor 2.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Sterol regulatory element-binding protein 2 (SREBF2) Antibody, Abbexa, abx241423
SREBF2 Antibody is a Rabbit Polyclonal against SREBF2.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, IHC
Conjugation
Unconjugated
Sterol regulatory element-binding protein 2 (SREBF2) Antibody, Abbexa, abx334108
SREBF2 Antibody is a Rabbit Polyclonal against SREBF2.
Host
Rabbit
Reactivity
Human
Applications
ELISA, IHC, IF/ICC
Conjugation
Unconjugated
Sterol regulatory element-binding protein 2 (SREBF2) Antibody, Abbexa, abx242399
SREBF2 Antibody is a Rabbit Polyclonal against SREBF2.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, IHC
Conjugation
Unconjugated
Sterol regulatory element-binding protein 2 (SREBF2) Antibody (FITC), Abbexa, abx337818
SREBF2 Antibody (FITC) is a Rabbit Polyclonal against SREBF2.
Host
Rabbit
Reactivity
Human
Applications
Conjugation
FITC
Sterol regulatory element-binding protein 2 (SREBF2) Antibody (HRP), Abbexa, abx337817
SREBF2 Antibody (HRP) is a Rabbit Polyclonal against SREBF2.
Host
Rabbit
Reactivity
Human
Applications
ELISA
Conjugation
HRP
Sterol regulatory element-binding protein 2 (SREBF2) Antibody (Biotin), Abbexa, abx337819
SREBF2 Antibody (Biotin) is a Rabbit Polyclonal against SREBF2.
Host
Rabbit
Reactivity
Human
Applications
ELISA
Conjugation
Biotin
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