Search results for Suppressor of Variegation 4-20 Homolog 2 (SUV4-20H2) Antibody
Suppressor of Variegation 4-20 Homolog 2 (SUV4-20H2) Antibody, Abbexa, abx026588
SUV420H2 and the related enzyme SUV420H1 (MIM 610881) function as histone methyltransferases that specifically trimethylate nucleosomal histone H4 (see MIM 602822) on lysine-20 (K20) (Schotta et al., 2004 [PubMed 15145825]).
Host
Rabbit
Reactivity
Mouse
Applications
ELISA, WB
Conjugation
Unconjugated
Suppressor of Variegation 4-20 Homolog 2 (SUV4-20H2) Antibody, Abbexa, abx032837
SUV420H2 is a histone methyltransferase that specifically trimethylates 'Lys-20' of histone H4. H4 'Lys-20' trimethylation represents a specific tag for epigenetic transcriptional repression. The protein mainly functions in pericentric heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin in these regions. SUV420H1 is targeted to histone H3 via its interaction with RB1 family proteins (RB1, RBL1 and RBL2).
Host
Rabbit
Reactivity
Human, Mouse
Applications
ELISA, WB, FCM
Conjugation
Unconjugated
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