Search results for Survival of Motor Neuron-Related-Splicing Factor 30 (SMNDC1) Antibody
Survival of Motor Neuron-Related-Splicing Factor 30 (SMNDC1) Antibody, Abbexa, abx302423
SMNDC1 Antibody is a Rabbit Polyclonal against SMNDC1.
Host
Rabbit
Reactivity
Human
Applications
ELISA, IHC, IP
Conjugation
Unconjugated
Survival of Motor Neuron-Related-Splicing Factor 30 (SMNDC1) Antibody, Abbexa, abx000816
SMNDC1 Antibody is a Rabbit Polyclonal antibody against SMNDC1. SPF30 (survival of motor neuron-related-splicing factor 30), also known as SMNDC1 (survival motor neuron domain containing 1) or SMNR (SMN-related protein), is an essential splicing factor required for spliceosome assembly that belongs to the SMN family. It contains one Tudor domain with significant similarity to SMN (Survival Motor Neuron) and is expressed in skeletal muscle, pancreas and heart, localizing to Cajal bodies and nuclear speckles. SPF30 plays an important role in spliceosome assembly and directly interacts with five U snRNPs. The loss of SPF30 causes spliceosome assembly to arrest at prespliceosomes (A complex). This supports a function for SPF30 in mediating the incorporation/recruitment of U4/U5/U6 tri-snRNP to the prespliceosome. In addition, the overexpression of SPF30 can lead to apoptosis.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB
Conjugation
Unconjugated
Survival of Motor Neuron-Related-Splicing Factor 30 (SMNDC1) Antibody, Abbexa, abx034342
This protein is a paralog of SMN1 gene, which encodes the survival motor neuron protein, mutations in which are cause of autosomal recessive proximal spinal muscular atrophy. The protein encoded by this gene is a nuclear protein that has been identified as a constituent of the spliceosome complex. This protein is differentially expressed, with abundant levels in skeletal muscle, and may share similar cellular function as the SMN1 gene.
Host
Rabbit
Reactivity
Human, Mouse
Applications
ELISA, WB, FCM
Conjugation
Unconjugated
Survival of Motor Neuron-Related-Splicing Factor 30 (SMNDC1) Antibody, Abbexa, abx238035
SMNDC1 Antibody is a Rabbit Polyclonal against SMNDC1.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Survival of Motor Neuron-Related-Splicing Factor 30 (SMNDC1) Antibody (HRP), Abbexa, abx305371
SMNDC1 Antibody (HRP) is a Rabbit Polyclonal against SMNDC1 conjugated to HRP.
Host
Rabbit
Reactivity
Human
Applications
ELISA
Conjugation
HRP
Survival of Motor Neuron-Related-Splicing Factor 30 (SMNDC1) Antibody (FITC), Abbexa, abx305372
SMNDC1 Antibody (FITC) is a Rabbit Polyclonal against SMNDC1 conjugated to FITC.
Host
Rabbit
Reactivity
Human
Applications
Conjugation
FITC
Survival of Motor Neuron-Related-Splicing Factor 30 (SMNDC1) Antibody (Biotin), Abbexa, abx305373
SMNDC1 Antibody (Biotin) is a Rabbit Polyclonal against SMNDC1 conjugated to Biotin.
Host
Rabbit
Reactivity
Human
Applications
ELISA
Conjugation
Biotin
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