Search results for Thrombopoietin Receptor / CD110 (MPL) Antibody
Thrombopoietin Receptor / CD110 (MPL) Antibody, Abbexa, abx327526
MPL Antibody is a Rabbit Polyclonal against MPL.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB
Conjugation
Unconjugated
Thrombopoietin Receptor / CD110 (MPL) Antibody, Abbexa, abx421014
Thrombopoietin Receptor / CD110 (MPL) Antibody is a Mouse Monoclonal antibody for the detection of Thrombopoietin Receptor / CD110 (MPL) in Human samples.
Host
Mouse
Reactivity
Human
Applications
FCM
Conjugation
Unconjugated
Thrombopoietin Receptor / CD110 (MPL) Antibody, Abbexa, abx455305
Thrombopoietin Receptor / CD110 (MPL) Antibody is a Rabbit polyclonal antibody for the detection of Human Thrombopoietin Receptor / CD110 (MPL).
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Thrombopoietin Receptor / CD110 (MPL) Antibody, Abbexa, abx104171
Polyclonal Antibody to Myeloproliferative Leukemia Virus Oncogene (MPL).
Host
Rabbit
Reactivity
Human
Applications
WB
Conjugation
Unconjugated
Thrombopoietin Receptor / CD110 (MPL) Antibody, Abbexa, abx312919
MPL Antibody is a Rabbit Polyclonal against MPL.
Host
Rabbit
Reactivity
Human
Applications
ELISA, IHC, IF/ICC
Conjugation
Unconjugated
Thrombopoietin Receptor / CD110 (MPL) Antibody, Abbexa, abx421013
Thrombopoietin Receptor / CD110 (MPL) Antibody is a Mouse Monoclonal antibody for the detection of Thrombopoietin Receptor / CD110 (MPL) in Human samples.
Host
Mouse
Reactivity
Human
Applications
FCM
Conjugation
Unconjugated
Thrombopoietin Receptor / CD110 (MPL) Antibody, Abbexa, abx104172
Polyclonal Antibody to Myeloproliferative Leukemia Virus Oncogene (MPL).
Host
Rabbit
Reactivity
Mouse
Applications
WB, IHC, IF/ICC
Conjugation
Unconjugated
Thrombopoietin Receptor / CD110 (MPL) Antibody, Abbexa, abx323336
MPL Antibody is a Rabbit Polyclonal against MPL.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB
Conjugation
Unconjugated
Thrombopoietin Receptor / CD110 (MPL) Antibody, Abbexa, abx011224
In 1990 an oncogene, v-mpl, was identified from the murine myeloproliferative leukemia virus that was capable of immortalizing bone marrow hematopoietic cells from different lineages. In 1992 the human homologue, named, c-mpl, was cloned. Sequence data revealed that c-mpl encoded a protein that was homologous with members of the hematopoietic receptor superfamily. Presence of anti-sense oligodeoxynucleotides of c-mpl inhibited megakaryocyte colony formation. The ligand for c-mpl, thrombopoietin, was cloned in 1994. Thrombopoietin was shown to be the major regulator of megakaryocytopoiesis and platelet formation. The protein encoded by the c-mpl gene, CD110, is a 635 amino acid transmembrane domain, with two extracellular cytokine receptor domains and two intracellular cytokine receptor box motifs. TPO-R deficient mice were severely thrombocytopenic, emphasizing the important role of CD110 and thrombopoietin in megakaryocyte and platelet formation. Upon binding of thrombopoietin CD110 is dimerized and the JAK family of non-receptor tyrosine kinases, as well as the STAT family, the MAPK family, the adaptor protein Shc and the receptors themselves become tyrosine phosphorylated.
Host
Mouse
Reactivity
Human
Applications
ELISA, FCM
Conjugation
Unconjugated
Thrombopoietin Receptor / CD110 (MPL) Antibody (FITC), Abbexa, abx312921
MPL Antibody (FITC) is a Rabbit Polyclonal against MPL conjugated to FITC.
Host
Rabbit
Reactivity
Human
Applications
Conjugation
FITC
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