Search results for Tisotumab

Tisotumab, Kyinno, KB-1327

Tisotumab, Abbexa, abx831361

Tisotumab is a monoclonal antibody biosimilar expressed in CHO cells, targeting F3/CD142, for use in laboratory research applications. This product is not suitable for use as medicines or in human, therapeutic or diagnostic applications.

Tisotumab ELISA Kit, Abbexa, abx395071

Tisotumab ELISA Kit is a quantitative ELISA kit for detection of Tisotumab.Tisotumab vedotin, also known as HuMax-TF, HuMax®-TF-ADC or TF-011-MMAE, is an antibody-drug conjugate (ADC) targeted to tissue factor (TF), a protein involved in tumor signaling and angiogenesis. Tisotumab vedotin includes an antibody targeting TF conjugated with monomethyl auristatin E (MMAE) via a cleavable maleimidocaproyl-valyl-citrullinyl-p-aminobenzyloxycarbonyl (mc-val-cit-PABC) type linker. Based on its high expression on many solid tumors (including ovarian, prostate, bladder, esophageal, endometrial and lung) and its rapid internalization, TF is considered a suitable target for antibody-drug conjugates. In pre-clinical trials tisotumab vedotin has shown strong ability to bind to TF and inhibit tumor growth. Genmab and Seattle Genetics are jointly developing tisotumab vedotin. In a Phase IIa study, preliminary data demonstrated a manageable safety profile and encouraging efficacy (ORR 37%) in relapsed, recurrent or metastatic cervical cancer.

Tisotumab ELISA Kit, ProteoGenix, KPTX182

Description of Tisotumab ELISA Kit The Structure of Tisotumab ELISA Kit Tisotumab is a monoclonal antibody that is used as a therapeutic target for the treatment of various types of cancer. It is derived from a mouse hybridoma cell line and is produced through recombinant DNA technology. The Tisotumab ELISA Kit is a diagnostic tool that is used to measure the levels of Tisotumab in biological samples. The kit is composed of several components, including microplates, Tisotumab-specific antibodies, enzyme-labeled secondary antibodies, and a substrate solution. The microplates are coated with a specific antibody that is designed to capture Tisotumab from the sample. The enzyme-labeled secondary antibody is used to detect the captured Tisotumab, and the substrate solution produces a color change that can be measured using a spectrophotometer. The Activity of Tisotumab ELISA Kit The Tisotumab ELISA Kit is a highly sensitive and specific tool for the detection and quantification of Tisotumab in biological samples. The kit utilizes the principle of sandwich ELISA, where the Tisotumab-specific antibodies are used to capture and detect the target protein in the sample. The Tisotumab ELISA Kit has a wide dynamic range, allowing for the detection of Tisotumab in both low and high concentrations. This makes it a valuable tool for monitoring the levels of Tisotumab in patients undergoing treatment. The kit also has a high level of reproducibility, ensuring consistent and reliable results. The Application of Tisotumab ELISA Kit The Tisotumab ELISA Kit has a wide range of applications in the field of cancer research and treatment. It is primarily used as a diagnostic tool to measure the levels of Tisotumab in biological samples, such as blood, serum, and plasma. This can help in the early detection of cancer and monitoring the response to treatment. In addition, the Tisotumab ELISA Kit can also be used to study the pharmacokinetics of Tisotumab, which is the process of how the body absorbs, distributes, and eliminates the drug. This information is crucial in determining the optimal dosage and treatment schedule for patients. Furthermore, the Tisotumab ELISA Kit can also be used in preclinical and clinical studies to evaluate the efficacy of Tisotumab as a therapeutic target. By measuring the levels of Tisotumab in different biological samples, researchers can assess the drug’s ability to reach its target and its effectiveness in treating cancer. Conclusion In summary, the Tisotumab ELISA Kit is a valuable tool for the detection and quantification of Tisotumab in biological samples. Its highly sensitive and specific nature, wide dynamic range, and reproducibility make it an essential tool in cancer research and treatment. With its various applications, the Tisotumab ELISA Kit plays a crucial role in advancing our understanding and treatment of cancer.

Tisotumab Biosimilar - Research Grade, ichor.bio, ICH5293

Detects human CD142

Research Grade Tisotumab (HB058016), abinScience, HB058016

Tisotumab Vedotin Biosimilar - Research Grade, ichor.bio, ICH5293V