Search results for Transcription Factor p65 / NFKB3 (RELA) Antibody
Transcription Factor p65 / NFKB3 (RELA) Antibody, Abbexa, abx031234
NFKB1 (MIM 164011) or NFKB2 (MIM 164012) is bound to REL (MIM 164910), RELA, or RELB (MIM 604758) to form the NFKB complex. The p50 (NFKB1) /p65 (RELA) heterodimer is the most abundant form of NFKB. The NFKB complex is inhibited by I-kappa-B proteins (NFKBIA, MIM 164008 or NFKBIB, MIM 604495), which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the I-kappa-B proteins by kinases (IKBKA, MIM 600664, or IKBKB, MIM 603258) marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NFKB complex. Activated NFKB complex translocates into the nucleus and binds DNA at kappa-B-binding motifs such as 5-prime GGGRNNYYCC 3-prime or 5-prime HGGARNYYCC 3-prime (where H is A, C, or T; R is an A or G purine; and Y is a C or T pyrimidine).
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB
Conjugation
Unconjugated
Transcription Factor p65 / NFKB3 (RELA) Antibody, Abbexa, abx326117
RELA Antibody is a Rabbit Polyclonal against RELA.
Host
Rabbit
Reactivity
Human, Mouse
Applications
ELISA, WB, IHC, IF/ICC
Conjugation
Unconjugated
Transcription Factor p65 / NFKB3 (RELA) Antibody, Abbexa, abx011267
Transcription Factor p65 (RELA) Antibody is a Rabbit Polyclonal antibody for the detection of p65/RELA. Nuclear factor k B (NF-kB) is a sequence-specific DNA-binding protein complex which regulates the expression of viral genomes, including the human immunodeficiency virus, and a variety of cellular genes, particularly those involved in immune and inflammatory responses. The members of the NF-Kb family in mammalian cells include the proto-oncogene c-Rel,p50/p105 (NFkB1), p65 (RelA), p52/p100 (NFkB2), and RelB. All of these proteins share a conserved 300-amino acid region known as the Rel homology domain which is responsible for DNA binding, dimerization, and nuclear translocation of NF-Kb. The p65 subunit is a major component of NF-Kb complexes and is responsible for trans-activation. NF-kappa-B heterodimeric p65-p50 and p65-c-Rel complexes are transcriptional activators. The NF-kappa-B p65-p65 complex appears to be involved in invasin-mediated activation of IL-8 expression. The inhibitory effect of I-kappa-B upon NF-kappa-B the cytoplasm is exerted primarily through the interaction with p65. p65 shows a weak DNA-binding site which could contribute directly to DNA binding in the NF-kappa-B complex. It associates with chromatin at the NF-kappa-B promoter region via association with DDX1.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IHC, IF/ICC
Conjugation
Unconjugated
Transcription Factor p65 / NFKB3 (RELA) Antibody, Abbexa, abx402296
Transcription Factor p65 (RELA) Antibody is a Recombinant Rabbit Monoclonal antibody for the detection of Human RELA.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IF/ICC, FCM
Conjugation
Unconjugated
Transcription Factor p65 / NFKB3 (RELA) Antibody, Abbexa, abx213487
RELA Antibody is a Rabbit Polyclonal against RELA.
Host
Rabbit
Reactivity
Human, Mouse
Applications
ELISA, WB
Conjugation
Unconjugated
Transcription Factor p65 / NFKB3 (RELA) Antibody, Abbexa, abx126472
RELA Antibody is a Rabbit Polyclonal against RELA.
Host
Rabbit
Reactivity
Human, Rat
Applications
ELISA, WB, IHC, IF/ICC
Conjugation
Unconjugated
Transcription Factor p65 / NFKB3 (RELA) Antibody, Abbexa, abx327405
RELA Antibody is a Rabbit Polyclonal against RELA.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB
Conjugation
Unconjugated
Transcription Factor p65 / NFKB3 (RELA) Antibody, Abbexa, abx159677
RELA Antibody is a Mouse Monoclonal against RELA.
Host
Mouse
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IP
Conjugation
Unconjugated
Transcription Factor p65 / NFKB3 (RELA) Antibody, Abbexa, abx031232
NFKB1 (MIM 164011) or NFKB2 (MIM 164012) is bound to REL (MIM 164910), RELA, or RELB (MIM 604758) to form the NFKB complex. The p50 (NFKB1) /p65 (RELA) heterodimer is the most abundant form of NFKB. The NFKB complex is inhibited by I-kappa-B proteins (NFKBIA, MIM 164008 or NFKBIB, MIM 604495), which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the I-kappa-B proteins by kinases (IKBKA, MIM 600664, or IKBKB, MIM 603258) marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NFKB complex. Activated NFKB complex translocates into the nucleus and binds DNA at kappa-B-binding motifs such as 5-prime GGGRNNYYCC 3-prime or 5-prime HGGARNYYCC 3-prime (where H is A, C, or T; R is an A or G purine; and Y is a C or T pyrimidine).
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IF/ICC
Conjugation
Unconjugated
Transcription Factor p65 / NFKB3 (RELA) Antibody, Abbexa, abx455829
Transcription Factor p65 (RELA) Antibody is a Rabbit polyclonal antibody for the detection of Human Transcription Factor p65 (RELA).
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
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