Search results for Tuberous Sclerosis Protein 2 (TSC2) Antibody
Tuberous Sclerosis Protein 2 (TSC2) Antibody, Abbexa, abx317842
TSC2 Antibody is a Rabbit Polyclonal against TSC2.
Host
Rabbit
Reactivity
Human, Mouse
Applications
ELISA, WB, IF/ICC
Conjugation
Unconjugated
Tuberous Sclerosis Protein 2 (TSC2) Antibody, Abbexa, abx328567
TSC2 Antibody is a Rabbit Polyclonal against TSC2.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Tuberous Sclerosis Protein 2 (TSC2) Antibody, Abbexa, abx031372
Mutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Tuberous Sclerosis Protein 2 (TSC2) Antibody, Abbexa, abx034676
In complex with TSC1, inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling. Acts as a GTPase-activating protein (GAP) for the small GTPase RHEB, a direct activator of the protein kinase activity of mTORC1. Implicated as a tumor suppressor. Involved in microtubule-mediated protein transport, but this seems to be due to unregulated mTOR signaling. Stimulates weakly the intrinsic GTPase activity of the Ras-related proteins RAP1A and RAB5 in vitro. Mutations in TSC2 lead to constitutive activation of RAP1A in tumors.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB
Conjugation
Unconjugated
Tuberous Sclerosis Protein 2 (TSC2) Antibody, Abbexa, abx329216
TSC2 Antibody is a Rabbit Polyclonal against TSC2.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IHC, IF/ICC
Conjugation
Unconjugated
Tuberous Sclerosis Protein 2 (TSC2) Antibody, Abbexa, abx127069
TSC2 Antibody is a Rabbit Polyclonal against TSC2.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
IF/ICC
Conjugation
Unconjugated
Tuberous Sclerosis Protein 2 (TSC2) Antibody, Abbexa, abx213738
TSC2 Antibody is a Rabbit Polyclonal against TSC2.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, IHC
Conjugation
Unconjugated
Tuberous Sclerosis Protein 2 (TSC2) Antibody, Abbexa, abx213927
TSC2 Antibody is a Rabbit Polyclonal against TSC2.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, IHC
Conjugation
Unconjugated
Tuberous Sclerosis Protein 2 (TSC2) Antibody, Abbexa, abx025288
Mutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms.
Host
Mouse
Reactivity
Mouse
Applications
ELISA, WB, IF/ICC
Conjugation
Unconjugated
Tuberous Sclerosis Protein 2 (TSC2) Antibody, Abbexa, abx326673
TSC2 Antibody is a Rabbit Polyclonal against TSC2.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, IHC
Conjugation
Unconjugated
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