Search results for Tumor Necrosis Factor Ligand Superfamily Member 11 / RANKL (TNFSF11) Antibody
Tumor Necrosis Factor Ligand Superfamily Member 11 / RANKL (TNFSF11) Antibody, Abbexa, abx239894
Tumor Necrosis Factor Ligand Superfamily Member 11 / RANKL (TNFSF11) Antibody is a Mouse Monoclonal antibody for the detection of RANKL. TNFSF11 also known as RANKL, is a member of the tumor necrosis factor (TNF) cytokine family which is a ligand for osteoprotegerin and functions as a key factor for osteoclast differentiation and activation. RANKL induces osteoclast formation through its receptor, RANK, which transduces signals by recruiting adaptor molecules, such as the TNF receptor-associated factor (TRAF) family of proteins. RANKL was shown to be a dentritic cell survival factor and is involved in the regulation of T cell-dependent immune response. T cell activation was reported to induce expression of this gene and lead to an increase of osteoclastogenesis and bone loss. RANKL was shown to activate antiapoptotic kinase AKT/PKB through a signaling complex involving SRC kinase and tumor necrosis factor receptor-associated factor (TRAF) 6, which indicated this protein may have a role in the regulation of cell apoptosis.
Host
Mouse
Reactivity
Human
Applications
ELISA, WB
Conjugation
Unconjugated
Tumor Necrosis Factor Ligand Superfamily Member 11 / RANKL (TNFSF11) Antibody, Abbexa, abx270204
Tumor Necrosis Factor Ligand Superfamily Member 11 / RANKL (TNFSF11) Antibody is a Mouse Monoclonal Antibody against Tumor Necrosis Factor Ligand Superfamily Member 11 / RANKL (TNFSF11) for use in flow cytometry.
Host
Mouse
Reactivity
Rat
Applications
FCM
Conjugation
Unconjugated
Tumor Necrosis Factor Ligand Superfamily Member 11 / RANKL (TNFSF11) Antibody, Abbexa, abx270212
Tumor Necrosis Factor Ligand Superfamily Member 11 / RANKL (TNFSF11) Antibody is a Mouse Monoclonal Antibody against Tumor Necrosis Factor Ligand Superfamily Member 11 / RANKL (TNFSF11) for use in flow cytometry.
Host
Mouse
Reactivity
Rat
Applications
FCM
Conjugation
Unconjugated
Tumor Necrosis Factor Ligand Superfamily Member 11 / RANKL (TNFSF11) Antibody, Abbexa, abx302190
TNFSF11 Antibody is a Rabbit Polyclonal against TNFSF11.
Host
Rabbit
Reactivity
Human
Applications
ELISA, IHC, IF/ICC
Conjugation
Unconjugated
Tumor Necrosis Factor Ligand Superfamily Member 11 / RANKL (TNFSF11) Antibody, Abbexa, abx110309
TNFSF11 Antibody is a Rabbit Polyclonal antibody against TNFSF11.
Host
Rabbit
Reactivity
Mouse
Applications
ELISA
Conjugation
Unconjugated
Tumor Necrosis Factor Ligand Superfamily Member 11 / RANKL (TNFSF11) Antibody, Abbexa, abx170078
Tumor Necrosis Factor Ligand Superfamily Member 11 / RANKL (TNFSF11) Antibody is a recombinant Mouse Monoclonal against TNFSF11.
Host
Mouse
Reactivity
Human
Applications
WB, IHC, IF/ICC, FCM
Conjugation
Unconjugated
Tumor Necrosis Factor Ligand Superfamily Member 11 / RANKL (TNFSF11) Antibody, Abbexa, abx104600
Polyclonal Antibody to TNFSF11 (TNFSF11).
Host
Rabbit
Reactivity
Human
Applications
WB, IHC, IF/ICC
Conjugation
Unconjugated
Tumor Necrosis Factor Ligand Superfamily Member 11 / RANKL (TNFSF11) Antibody, Abbexa, abx327473
TNFSF11 Antibody is a Rabbit Polyclonal against TNFSF11.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB
Conjugation
Unconjugated
Tumor Necrosis Factor Ligand Superfamily Member 11 / RANKL (TNFSF11) Antibody, Abbexa, abx001988
TNFSF11 Antibody is a Rabbit Polyclonal antibody against TNFSF11. This gene encodes a member of the tumor necrosis factor (TNF) cytokine family which is a ligand for osteoprotegerin and functions as a key factor for osteoclast differentiation and activation. This protein was shown to be a dentritic cell survival factor and is involved in the regulation of T cell-dependent immune response. T cell activation was reported to induce expression of this gene and lead to an increase of osteoclastogenesis and bone loss. This protein was shown to activate antiapoptotic kinase AKT/PKB through a signaling complex involving SRC kinase and tumor necrosis factor receptor-associated factor (TRAF) 6, which indicated this protein may have a role in the regulation of cell apoptosis. Targeted disruption of the related gene in mice led to severe osteopetrosis and a lack of osteoclasts. The deficient mice exhibited defects in early differentiation of T and B lymphocytes, and failed to form lobulo-alveolar mammary structures during pregnancy. Two alternatively spliced transcript variants have been found.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB, IF/ICC
Conjugation
Unconjugated
Tumor Necrosis Factor Ligand Superfamily Member 11 / RANKL (TNFSF11) Antibody, Abbexa, abx131778
TNFSF11 Antibody is a Mouse Monoclonal against TNFSF11.
Host
Mouse
Reactivity
Rat
Applications
WB, IHC, IF/ICC
Conjugation
Unconjugated
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