Search results for Tyrosine Kinase Non Receptor 1 (TNK1) Antibody
Tyrosine Kinase Non Receptor 1 (TNK1) Antibody, Abbexa, abx012267
TNK1: tyrosine kinase, non-receptor, 1. TNK1 is a nonreceptor tyrosine kinase (NRPTK). These kinases, like members of the SRC (MIM 190090) and JAK (see MIM 147795) families, mediate intracellular signaling downstream of receptor activation.Tnk1 is a ubiquitously expressed 47-kDa protein with autotyrosine kinase activity that is developmentally regulated during embryogenesis. Tnk1 is also upregulated following IL3 withdrawal from factor-dependent murine NSF/N1.H7 cells that undergo apoptosis, suggesting a role in growth inhibition. Data support a negative regulatory role for Tnk1 in regulating the Ras-Raf1-MAPK growth pathway by a mechanism that requires its autotyrosine kinase activity.
Host
Mouse
Reactivity
Human
Applications
ELISA
Conjugation
Unconjugated
Tyrosine Kinase Non Receptor 1 (TNK1) Antibody, Abbexa, abx025220
Involved in negative regulation of cell growth. Has tumor suppressor properties. Plays a negative regulatory role in the Ras-MAPK pathway. May function in signaling pathways utilized broadly during fetal development and more selectively in adult tissues and in cells of the lymphohematopoietic system. Could specifically be involved in phospholipid signal transduction.
Host
Mouse
Reactivity
Mouse
Applications
ELISA, WB
Conjugation
Unconjugated
Tyrosine Kinase, Non-Receptor, 1 (TNK1) Antibody, Abbexa, abx116390
Tyrosine Kinase, Non-Receptor, 1 Antibody is a Rabbit Polyclonal antibody against Tyrosine Kinase, Non-Receptor, 1.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Tyrosine Kinase Non Receptor 1 (TNK1) Antibody, Abbexa, abx238833
TNK1 Antibody is a Rabbit Polyclonal against TNK1.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Tyrosine Kinase Non Receptor 1 (TNK1) Antibody, Abbexa, abx025131
Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Tyrosine Kinase Non Receptor 1 (TNK1) Antibody, Abbexa, abx025132
Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB
Conjugation
Unconjugated
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