Search results for Tyrosine-protein kinase ABL1
Tyrosine-Protein Kinase ABL1 (ABL1) Antibody, Abbexa, abx329997
Tyrosine-Protein Kinase ABL1 (ABL1) Antibody is a Rabbit Polyclonal against Tyrosine-Protein Kinase ABL1 (ABL1).
Host
Rabbit
Reactivity
Human, Mouse, Rat, Monkey
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Tyrosine-Protein Kinase ABL1 (ABL1) Antibody, Abbexa, abx110321
Tyrosine-Protein Kinase ABL1 Antibody is a Rabbit Polyclonal antibody against Tyrosine-Protein Kinase ABL1.
Host
Rabbit
Reactivity
Human
Applications
ELISA, IHC, IP
Conjugation
Unconjugated
Tyrosine-Protein Kinase ABL1 (ABL1) Antibody, Abbexa, abx329360
Tyrosine-Protein Kinase ABL1 (ABL1) Antibody is a Rabbit Polyclonal against Tyrosine-Protein Kinase ABL1 (ABL1).
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IHC, IF/ICC
Conjugation
Unconjugated
Tyrosine-Protein Kinase ABL1 (ABL1) Antibody, Abbexa, abx326403
Tyrosine-Protein Kinase ABL1 (ABL1) Antibody is a Rabbit Polyclonal against Tyrosine-Protein Kinase ABL1 (ABL1).
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, IHC
Conjugation
Unconjugated
Tyrosine-Protein Kinase ABL1 (ABL1) Antibody, Abbexa, abx329854
Tyrosine-Protein Kinase ABL1 (ABL1) Antibody is a Rabbit Polyclonal against Tyrosine-Protein Kinase ABL1 (ABL1).
Host
Rabbit
Reactivity
Human, Mouse, Rat, Monkey
Applications
ELISA, WB
Conjugation
Unconjugated
Tyrosine-Protein Kinase ABL1 (ABL1) Antibody, Abbexa, abx033626
The Tyrosine-Protein Kinase ABL1 (ABL1) protooncogene encodes a cytoplasmic and nuclear protein tyrosine kinase that has been implicated in processes of cell differentiation, cell division, cell adhesion, and stress response. Activity of c-Abl protein is negatively regulated by its SH3 domain, and deletion of the SH3 domain turns Tyrosine-Protein Kinase ABL1 (ABL1) into an oncogene. The t (9;22) translocation results in the head-to-tail fusion of the BCR and Tyrosine-Protein Kinase ABL1 (ABL1) genes present in many cases of chronic myelogeneous leukemia. The DNA-binding activity of the ubiquitously expressed Tyrosine-Protein Kinase ABL1 (ABL1) tyrosine kinase is regulated by CDC2-mediated phosphorylation, suggesting a cell cycle function for Tyrosine-Protein Kinase ABL1 (ABL1).
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB
Conjugation
Unconjugated
Tyrosine-Protein Kinase ABL1 (ABL1) Antibody, Abbexa, abx119028
Tyrosine-Protein Kinase ABL1 (ABL1) Antibody is a Rabbit Polyclonal antibody against Tyrosine-Protein Kinase ABL1 (ABL1).
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB
Conjugation
Unconjugated
Tyrosine-Protein Kinase ABL1 (ABL1) Antibody, Abbexa, abx212830
Tyrosine-Protein Kinase ABL1 (ABL1) Antibody is a Rabbit Polyclonal against Tyrosine-Protein Kinase ABL1 (ABL1).
Host
Rabbit
Reactivity
Human, Mouse
Applications
ELISA, IHC
Conjugation
Unconjugated
Tyrosine-Protein Kinase ABL1 (Abl1) Antibody, Abbexa, abx027683
Protein kinase that regulates key processes linked to cell growth and survival. Regulates cytoskeleton remodeling during cell differentiation, cell division and cell adhesion. Localizes to dynamic actin structures, and phosphorylates CRK and CRKL, DOK1, and other proteins controlling cytoskeleton dynamics. Regulates DNA repair potentially by activating the proapoptotic pathway when the DNA damage is too severe to be repaired. Phosphorylates PSMA7 that leads to an inhibition of proteasomal activity and cell cycle transition blocks.
Host
Rabbit
Reactivity
Mouse
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Tyrosine-Protein Kinase ABL1 (ABL1) Antibody, Abbexa, abx000665
Tyrosine-Protein Kinase ABL1 (ABL1) Antibody is a Rabbit Polyclonal antibody against Tyrosine-Protein Kinase ABL1 (ABL1). This gene is a protooncogene that encodes a protein tyrosine kinase involved in a variety of cellular processes, including cell division, adhesion, differentiation, and response to stress. The activity of the protein is negatively regulated by its SH3 domain, whereby deletion of the region encoding this domain results in an oncogene. The ubiquitously expressed protein has DNA-binding activity that is regulated by CDC2-mediated phosphorylation, suggesting a cell cycle function. This gene has been found fused to a variety of translocation partner genes in various leukemias, most notably the t(9;22) translocation that results in a fusion with the 5' end of the breakpoint cluster region gene (BCR; MIM:151410). Alternative splicing of this gene results in two transcript variants, which contain alternative first exons that are spliced to the remaining common exons.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IHC, IF/ICC
Conjugation
Unconjugated
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