Search results for Ubiquitin Carboxyl-Terminal Hydrolase 11 (USP11) Antibody
Ubiquitin Carboxyl-Terminal Hydrolase 11 (USP11) Antibody, Abbexa, abx430631
USP11 Antibody is a Goat Polyclonal antibody against USP11.
Host
Goat
Reactivity
Human
Applications
P-ELISA, WB
Conjugation
Unconjugated
Ubiquitin Carboxyl-Terminal Hydrolase 11 (USP11) Antibody, Abbexa, abx149788
Ubiquitin Carboxyl-Terminal Hydrolase 11 (USP11) Antibody is a Rabbit Polyclonal antibody for the detection of USP11. Protease that can remove conjugated ubiquitin from target proteins and polyubiquitin chains (PubMed:12084015, PubMed:15314155, PubMed:17897950, PubMed:19874889, PubMed:20233726, PubMed:24724799). Inhibits the degradation of target proteins by the proteasome (PubMed:12084015). Cleaves preferentially 'Lys-6' and 'Lys-63'-linked ubiquitin chains. Has lower activity with 'Lys-11' and 'Lys-33'-linked ubiquitin chains, and extremely low activity with 'Lys-27', 'Lys-29' and 'Lys-48'-linked ubiquitin chains (in vitro) (PubMed:24724799). Plays a role in the regulation of pathways leading to NF-kappa-B activation (PubMed:17897950, PubMed:19874889). Plays a role in the regulation of DNA repair after double-stranded DNA breaks (PubMed:15314155, PubMed:20233726).
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC, IP
Conjugation
Unconjugated
Ubiquitin Carboxyl-Terminal Hydrolase 11 (USP11) Antibody, Abbexa, abx455507
Ubiquitin Carboxyl-Terminal Hydrolase 11 (USP11) Antibody is a Rabbit polyclonal antibody for the detection of Human Ubiquitin Carboxyl-Terminal Hydrolase 11 (USP11).
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Ubiquitin Carboxyl-Terminal Hydrolase 11 (USP11) Antibody, Abbexa, abx031547
Modification of target proteins by ubiquitin participates in a wide array of biological functions. Proteins destined for degradation or processing via the 26 S proteasome are coupled to multiple copies of ubiquitin. However, attachment of ubiquitin or ubiquitin-related molecules may also result in changes in subcellular distribution or modification of protein activity. An additional level of ubiquitin regulation, deubiquitination, is catalyzed by proteases called deubiquitinating enzymes, which fall into four distinct families. Ubiquitin C-terminal hydrolases, ubiquitin-specific processing proteases (USPs), 1 OTU-domain ubiquitin-aldehyde-binding proteins, and Jab1/Pad1/MPN-domain-containing metallo-enzymes. Among these four families, USPs represent the most widespread and represented deubiquitinating enzymes across evolution. USPs tend to release ubiquitin from a conjugated protein. They display similar catalytic domains containing conserved Cys and His boxes but divergent N-terminal and occasionally C-terminal extensions, which are thought to function in substrate recognition, subcellular localization, and protein-protein interactions.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Ubiquitin Carboxyl-Terminal Hydrolase 11 (USP11) Antibody, Abbexa, abx239305
USP11 Antibody is a Rabbit Polyclonal against USP11.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC, IF/ICC, IP
Conjugation
Unconjugated
Ubiquitin Carboxyl-Terminal Hydrolase 11 (USP11) Antibody, Abbexa, abx014971
Rabbit polyclonal antibody against USP11 protein. Immunogen region is Internal.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB
Conjugation
Unconjugated
Ubiquitin carboxyl-terminal hydrolase 11 (USP11) Antibody, Abbexa, abx327684
USP11 Antibody is a Rabbit Polyclonal against USP11.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB
Conjugation
Unconjugated
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