Search results for Ubiquitin Carboxyl-Terminal Hydrolase 14 (USP14) Antibody
Ubiquitin Carboxyl-Terminal Hydrolase 14 (USP14) Antibody, Abbexa, abx031550
Modification of target proteins by ubiquitin participates in a wide array of biological functions. Proteins destined for degradation or processing via the 26 S proteasome are coupled to multiple copies of ubiquitin. However, attachment of ubiquitin or ubiquitin-related molecules may also result in changes in subcellular distribution or modification of protein activity. An additional level of ubiquitin regulation, deubiquitination, is catalyzed by proteases called deubiquitinating enzymes, which fall into four distinct families. Ubiquitin C-terminal hydrolases, ubiquitin-specific processing proteases (USPs), 1 OTU-domain ubiquitin-aldehyde-binding proteins, and Jab1/Pad1/MPN-domain-containing metallo-enzymes. Among these four families, USPs represent the most widespread and represented deubiquitinating enzymes across evolution. USPs tend to release ubiquitin from a conjugated protein. They display similar catalytic domains containing conserved Cys and His boxes but divergent N-terminal and occasionally C-terminal extensions, which are thought to function in substrate recognition, subcellular localization, and protein-protein interactions.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Ubiquitin Carboxyl-Terminal Hydrolase 14 (USP14) Antibody, Abbexa, abx455556
Ubiquitin Carboxyl-Terminal Hydrolase 14 (USP14) Antibody is a Rabbit polyclonal antibody for the detection of Human Ubiquitin Carboxyl-Terminal Hydrolase 14 (USP14).
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Ubiquitin Carboxyl-Terminal Hydrolase 14 (USP14) Antibody, Abbexa, abx402330
Ubiquitin Carboxyl-Terminal Hydrolase 14 (USP14) Antibody is a Recombinant Rabbit Monoclonal antibody for the detection of Human USP14.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IF/ICC
Conjugation
Unconjugated
Ubiquitin Carboxyl-Terminal Hydrolase 14 (USP14) Antibody, Abbexa, abx031278
This gene encodes a member of the ubiquitin-specific processing (UBP) family of proteases that is a deubiquitinating enzyme (DUB) with His and Cys domains. This protein is located in the cytoplasm and cleaves the ubiquitin moiety from ubiquitin-fused precursors and ubiquitinylated proteins. Mice with a mutation that results in reduced expression of the ortholog of this protein are retarded for growth, develop severe tremors by 2 to 3 weeks of age followed by hindlimb paralysis and death by 6 to 10 weeks of age. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB
Conjugation
Unconjugated
Ubiquitin Carboxyl-Terminal Hydrolase 14 (USP14) Antibody, Abbexa, abx037633
Rabbit Polyclonal against the Ubiquitin Carboxyl-Terminal Hydrolase 14 (USP14) protein.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Ubiquitin Carboxyl-Terminal Hydrolase 14 (USP14) Antibody, Abbexa, abx116428
Ubiquitin Specific Peptidase 14 (Trna-Guanine Transglycosylase) Antibody is a Rabbit Polyclonal antibody against Ubiquitin Specific Peptidase 14 (Trna-Guanine Transglycosylase).
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IF/ICC
Conjugation
Unconjugated
Ubiquitin Carboxyl-Terminal Hydrolase 14 (USP14) Antibody, Abbexa, abx034916
Proteasome-associated deubiquitinase which releases ubiquitin from the proteasome targeted ubiquitinated proteins. Ensures the regeneration of ubiquitin at the proteasome. Is a reversibly associated subunit of the proteasome and a large fraction of proteasome-free protein exists within the cell. Required for the degradation of the chemokine receptor CXCR4 which is critical for CXCL12-induced cell chemotaxis. Serves also as a physiological inhibitor of endoplasmic reticulum-associated degradation (ERAD) under the non-stressed condition by inhibiting the degradation of unfolded endoplasmic reticulum proteins via interaction with ERN1. Indispensable for synaptic development and function at neuromuscular junctions (NMJs).
Host
Mouse
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB
Conjugation
Unconjugated
Ubiquitin Carboxyl-Terminal Hydrolase 14 (USP14) Antibody, Abbexa, abx239310
Ubiquitin Carboxyl-Terminal Hydrolase 14 (USP14) Antibody is a Rabbit Polyclonal against Ubiquitin Carboxyl-Terminal Hydrolase 14 (USP14).
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IF/ICC, FCM
Conjugation
Unconjugated
Ubiquitin Carboxyl-Terminal Hydrolase 14 (USP14) Antibody, Abbexa, abx110327
Ubiquitin carboxyl-terminal hydrolase 14 Antibody is a Rabbit Polyclonal antibody against Ubiquitin carboxyl-terminal hydrolase 14.
Host
Rabbit
Reactivity
Human, Mouse
Applications
ELISA, WB, IHC, IF/ICC
Conjugation
Unconjugated
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