Search results for Ubiquitin Carboxyl-Terminal Hydrolase BAP1 (BAP1) Antibody
Ubiquitin Carboxyl-Terminal Hydrolase BAP1 (BAP1) Antibody, Abbexa, abx005012
BAP1 Antibody is a Rabbit Polyclonal antibody against BAP1. This gene belongs to the ubiquitin C-terminal hydrolase subfamily of deubiquitinating enzymes that are involved in the removal of ubiquitin from proteins. The encoded enzyme binds to the breast cancer type 1 susceptibility protein (BRCA1) via the RING finger domain of the latter and acts as a tumor suppressor. In addition, the enzyme may be involved in regulation of transcription, regulation of cell cycle and growth, response to DNA damage and chromatin dynamics. Germline mutations in this gene may be associated with tumor predisposition syndrome (TPDS), which involves increased risk of cancers including malignant mesothelioma, uveal melanoma and cutaneous melanoma.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB, IHC, IF/ICC
Conjugation
Unconjugated
Ubiquitin Carboxyl-Terminal Hydrolase BAP1 (BAP1) Antibody, Abbexa, abx230800
BAP1 Antibody is a Rabbit Polyclonal against BAP1.
Host
Rabbit
Reactivity
Human, Mouse
Applications
ELISA, WB
Conjugation
Unconjugated
Ubiquitin Carboxyl-Terminal Hydrolase BAP1 (BAP1) Antibody, Abbexa, abx111253
Brca1 Associated Protein-1 (Ubiquitin Carboxy-Terminal Hydrolase) Antibody is a Rabbit Polyclonal antibody against Brca1 Associated Protein-1 (Ubiquitin Carboxy-Terminal Hydrolase).
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB
Conjugation
Unconjugated
Ubiquitin Carboxyl-Terminal Hydrolase BAP1 (BAP1) Antibody, Abbexa, abx036098
Rabbit Polyclonal against the BAP1 protein.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Ubiquitin Carboxyl-Terminal Hydrolase BAP1 (BAP1) Antibody, Abbexa, abx031561
BRCA1-associated protein-1, ' or BAP1 interacts with the RING finger domain of BRCA1. The N-terminal 240 amino acids of the predicted 729-amino acid human protein show homology to ubiquitin C-terminal hydrolases (UCHs), thiol proteases that catalyze proteolytic processing of ubiquitin. In addition, BAP1 contains an acidic region, a highly charged C-terminal region, and 2 putative nuclear localization signals. BAP1 and BRCA1 associate in vivo and have overlapping subnuclear localization patterns.1 BAP1 enhances BRCA1-mediated inhibition of breast cancer cell growth. Northern blot analysis indicates that BAP1 is expressed as a 4-kb mRNA in all human tissues tested, with A 4.8-kb transcript expressed exclusively in testis. Northern blot analysis and in situ hybridization reveal that BAP1 and BRCA1 are coexpressed during murine breast development and remodeling. The BAP1 gene has been mapped to 3p21.3, a region of loss of heterozygosity for breast cancer as well as frequently deleted in lung carcinomas.1 Intragenic homozygous rearrangements and deletions of BAP1 appear in lung carcinoma cell lines. It has been postulated that BAP1 is a tumor suppressor gene that functions in the BRCA1 growth control pathway.1.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IHC, IF/ICC, FCM
Conjugation
Unconjugated
Ubiquitin Carboxyl-Terminal Hydrolase BAP1 (BAP1) Antibody, Abbexa, abx242072
BAP1 Antibody is a Rabbit Polyclonal against BAP1.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Ubiquitin Carboxyl-Terminal Hydrolase BAP1 (BAP1) Antibody, Abbexa, abx321413
BAP1 Antibody is a Rabbit Polyclonal against BAP1.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB
Conjugation
Unconjugated
Ubiquitin Carboxyl-Terminal Hydrolase BAP1 (BAP1) Antibody, Abbexa, abx375806
Ubiquitin Carboxyl-Terminal Hydrolase BAP1 (BAP1) Antibody is a Rabbit Polyclonal antibody against Ubiquitin Carboxyl-Terminal Hydrolase BAP1 (BAP1).
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB
Conjugation
Unconjugated
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