Search results for Urokinase Plasminogen Activator Surface Receptor / uPAR / CD87 (PLAUR) Antibody
Urokinase Plasminogen Activator Surface Receptor / uPAR / CD87 (PLAUR) Antibody, Abbexa, abx110670
Urokinase plasminogen activator surface receptor Antibody is a Rabbit Polyclonal antibody against Urokinase plasminogen activator surface receptor.
Host
Rabbit
Reactivity
Human, Rat
Applications
ELISA, WB
Conjugation
Unconjugated
Urokinase Plasminogen Activator Surface Receptor / uPAR / CD87 (PLAUR) Antibody, Abbexa, abx211253
PLAUR Antibody is a Rabbit Polyclonal against PLAUR.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Urokinase Plasminogen Activator Surface Receptor / uPAR / CD87 (PLAUR) Antibody, Abbexa, abx318558
PLAUR Antibody is a Rabbit Polyclonal against PLAUR.
Host
Rabbit
Reactivity
Human, Mouse
Applications
ELISA, WB, IHC, IF/ICC
Conjugation
Unconjugated
Urokinase Plasminogen Activator Surface Receptor / uPAR / CD87 (PLAUR) Antibody, Abbexa, abx140374
CD87 Antibody is a Mouse Monoclonal against CD87.
Host
Mouse
Reactivity
Human
Applications
FCM
Conjugation
Unconjugated
Urokinase Plasminogen Activator Surface Receptor / uPAR / CD87 (PLAUR) Antibody, Abbexa, abx146428
PLAUR Antibody is a Rabbit Polyclonal against PLAUR.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Urokinase Plasminogen Activator Surface Receptor / uPAR / CD87 (PLAUR) Antibody, Abbexa, abx211254
PLAUR Antibody is a Rabbit Polyclonal against PLAUR.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Urokinase Plasminogen Activator Surface Receptor / uPAR / CD87 (PLAUR) Antibody, Abbexa, abx001219
PLAUR Antibody is a Rabbit Polyclonal antibody against PLAUR. Urokinase plasminogen activator surface receptor (uPAR, also known as PLAUR or CD87) is a 45-65 kDa, highly glycosylated, GPI-anchored membrane protein. It contains three homologous domains (D1-D3) of which the N-terminal one (D1) represents the uPA-binding domain. After binding to uPAR, urokinase plasminogen activator (uPA) cleaves plasminogen, generating the active protease plasmin which is involved in a wide variety of physiologic and pathologic processes. In addition to regulating proteolysis, uPAR has important function in cell adhesion, migration and proliferation. Studies reveal that uPAR expression is elevated during inflammation and tissue remodelling and in many human cancers, in which it frequently indicates poor prognosis. (PMID 20027185; 12461559).
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB
Conjugation
Unconjugated
Urokinase Plasminogen Activator Surface Receptor / uPAR / CD87 (PLAUR) Antibody, Abbexa, abx033919
The urokinase-type plasminogen activator receptor is a key molecule in the regulation of cell-surface plasminogen activation and plays an important role in many normal as well as pathologic processes. The human PLAUR cDNA encodes 335 amino acids including a predicted signal peptide of 22 residues and a hydrophobic C-terminal portion.1 It produces a highly glycosylated protein of about 50 kD in monocytes where it is anchored to the plasma membrane by glycosyl-phosphatidylinositol linkage. PLAUR, also known as UPAR, is directly associated with the carbohydrate-binding domain of SELL in the membrane of neutrophils, an association analogous to that between PLAUR and beta-2 integrins.2 PLAUR-mediated calcium mobilization is SELL dependent. UPAR mRNA levels correlate with the invasive potential of endometrial carcinomas and show a 33-fold increase in UPAR mRNA levels in advanced clinical stage endometrial tumors compared with normal endometrial tissue.3 Furthermore, the increase in UPAR mRNA levels correlated linearly with the progression of disease stage. UPAR protein expressioin correlated positively with rate of recurrence and mortality in patients with endometrial cancer.4 UPAR appears to be a useful prognostic marker for advanced endometrial cancer.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Urokinase Plasminogen Activator Surface Receptor / uPAR / CD87 (PLAUR) Antibody (HRP), Abbexa, abx306409
PLAUR Antibody (HRP) is a Rabbit Polyclonal against PLAUR conjugated to HRP.
Host
Rabbit
Reactivity
Human
Applications
ELISA
Conjugation
HRP
Urokinase Plasminogen Activator Surface Receptor / uPAR / CD87 (PLAUR) Antibody (FITC), Abbexa, abx306410
PLAUR Antibody (FITC) is a Rabbit Polyclonal against PLAUR conjugated to FITC.
Host
Rabbit
Reactivity
Human
Applications
Conjugation
FITC
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