Search results for Ustekinumab

Ustekinumab Biosimilar – Anti-Human IL-12 IL-23 mAb – Research Grade, ProteoGenix, PX-TA1011

Description of Ustekinumab Biosimilar - Anti-Human IL-12 IL-23 mAb - Research Grade General information about Ustekinumab Ustekinumab is a human monoclonal antibody used to treat psoriasis. It is also approved to treat Crohn’s disease and ulcerative colitis among people who have not responded to more traditional treatments. It is a subcutaneous human interleukin 12 and interleukin 23 antagonist. These are naturally occurring proteins that regulate the immune system and immune-mediated inflammatory disorders. This product is for research use only.

Ustekinumab, Kyinno, KB-1377

Ustekinumab, Affinityimmuno, ab-131-ustekinumab

Ustekinumab, Abbexa, abx831085

Ustekinumab is a monoclonal antibody biosimilar expressed in CHO cells, targeting IL12B, for use in laboratory research applications. This product is not suitable for use as medicines or in human, therapeutic or diagnostic applications. Ustekinumab is a human immunoglobulin (Ig) G1 kappa monoclonal antibody directed against interleukin(IL)-12 and IL-23, which are cytokines that are involved in immune and inflammatory responses. 2 It was generated via recombinant human IL-12 immunization of human Ig (hu-Ig) transgenic mice. 2 It is a targeted biologic disease-modifying anti-rheumatic drug (bDMARDs) that is used in the management of various inflammatory conditions that involve the activation of IL-12 and IL-23 signalling pathways. Interleukin (IL)-12 and IL-23 are heterodimeric cytokines that evoke immune and inflammatory responses, such as natural killer cell activation and CD4+ T-cell differentiation and activation. The role of IL-12 and IL-23 were implicated in a variety of chronic inflammatory conditions, such as psoriasis and inflammatory bowel diseases. They modulate lymphocyte function, including T-helper (Th) 1 and Th17 cell subsets, 2 as CD4+ T cells can differentiate into T-helper (Th) effector lineages based on the environment. Th cells can further activate the downstream pro-inflammatory mediators and transcription factors such as TNFα and IFNγ that drive innate and adaptive immunity.

Ustekinumab Antibody, Abbexa, abx376599

Ustekinumab Antibody is a rabbit polyclonal antibody for the detection of Ustekinumab.

Human Anti-Ustekinumab Antibody (Anti-Ustekinumab) ELISA Kit, Abbexa, abx392513

Human Anti-Ustekinumab Antibody (Anti-Ustekinumab) ELISA Kit is an ELISA Kit against Anti-Ustekinumab Antibody (Anti-Ustekinumab).

Ustekinumab ELISA Kit, Abbexa, abx392579

Ustekinumab ELISA Kit is a quantitative ELISA kit for detection of Ustekinumab.

Anti-Ustekinumab Polyclonal Antibody, AntibodySystem, PAD84001

Ustekinumab Biosimilar - Research Grade, ichor.bio, ICH4034

Detects human IL-12 and IL-23. This non-therapeutic antibody uses the same sequence as the therapeutic antibody Ustekinumab.

Research Grade Ustekinumab (HB769016), abinScience, HB769016