Search results for Vitamin K-dependent protein Z
Vitamin K-Dependent Protein Z (PROZ) Antibody, Abbexa, abx016049
PROZ protein Z, vitamin K-dependent plasma glycoprotein.It is 62 kDa large and 396 amino acids long.It has four domains: a gla-rich region, two EGF-like domains and a trypsin-like domain.It lacks the serine residue that would make it catalytically active as a serine protease.It is a member of the coagulation cascade, the group of blood proteins that leads to the formation of blood clots.It is vitamin K-dependent, and its functionality is therefore impaired in warfarin therapy.It is a glycoprotein.Although it is not enzymatically active, it is structurally related to several serine proteases of the coagulation cascade: factors VII, IX, X and protein C.The carboxyglutamate residues (which require vitamin K) bind protein Z to phospholipid surfaces.The main role of protein Z appears to be the degradation of factor Xa.This is done by protein Z-related protease inhibitor (ZPI), but the reaction is accelerated 1000-fold by the presence of protein Z.Oddly, ZPI also degrades factor XI, but this reaction does not require the presence of protein Z.In some studies, deficiency states have been associated with a propensity to thrombosis.Others, however, link it to bleeding tendency; there is no clear explanation for this, as it acts physiologically as an inhibitor, and deficiency would logically have led to a predisposition for thrombosis.
Host
Mouse
Reactivity
Human
Applications
ELISA, WB
Conjugation
Unconjugated
Human Vitamin K-dependent protein Z (PROZ) ELISA Kit, Abbkine, KTE61119
• Do not mix components from different kit lots or use reagents beyond the kit expiration date.• Allow all reagents to warm to room temperature for at least 30 minutes before opening.• Pre-rinse the pipet tip with reagent, use fresh pipet tips for each sample, standard and reagent to avoid contamination. • Unused wells must be kept desiccated at 4 °C in the sealed bag provided.• Mix Thoroughly is very important for the result. It is recommended using low frequency oscillator or slight hand shaking every 10 minutes.• It is recommended that all samples and standards be assayed in duplicate or triplicate.
Host
Reactivity
Applications
Conjugation
Cow Vitamin K-dependent protein Z (PROZ) ELISA Kit, Abbexa, abx513874
Cow Vitamin K-dependent protein Z (PROZ) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Cow Vitamin K-dependent protein Z concentrations in serum, plasma and other biological fluids.
Host
Reactivity
Cow
Applications
ELISA
Conjugation
Protein Z Antibody (YA5029), MedChemexpress, HY-P85337
Protein Z Antibody (YA5029) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to Protein Z.
Host
Mouse
Reactivity
Human
Applications
WB
Conjugation
Non-conjugated
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