Search results for WW Domain Containing Transcription Regulator Protein 1 (WWTR1) Antibody
WW Domain-Containing Transcription Regulator Protein 1 (WWTR1) Antibody, Abbexa, abx457065
WW Domain-Containing Transcription Regulator Protein 1 (WWTR1) Antibody is a Rabbit polyclonal antibody for the detection of Human WW Domain-Containing Transcription Regulator Protein 1 (WWTR1).
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
WW Domain Containing Transcription Regulator Protein 1 (WWTR1) Antibody, Abbexa, abx028805
Transcriptional coactivator which acts as a downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. WWTR1 enhances PAX8 and NKX2-1/TTF1-dependent gene activation. Regulates the nuclear accumulation of SMADS and has a key role in coupling them to the transcriptional machinery such as the mediator complex. Regulates embryonic stem-cell self-renewal, promotes cell proliferation and epithelial-mesenchymal transition.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB
Conjugation
Unconjugated
WW Domain Containing Transcription Regulator Protein 1 (WWTR1) Antibody, Abbexa, abx006098
WWTR1 Antibody is a Rabbit Polyclonal Antibody against WWTR1.
Host
Rabbit
Reactivity
Human, Mouse
Applications
IF/ICC
Conjugation
Unconjugated
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