Search results for abx000147

Mdm2 p53 Binding Protein Homolog Phospho-Ser260 (MDM2 pS260) Antibody, Abbexa, abx000147

MDM2 (pS260) Antibody is a Rabbit Polyclonal antibody against MDM2 (pS260). This gene encodes a nuclear-localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. This gene is itself transcriptionally-regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript variants, many of which may be expressed only in tumor cells.